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HIV clinical trials

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NCT ID: NCT06468995 Not yet recruiting - HIV Clinical Trials

Antiviral Long Acting Drugs Landing in People Living With HIV

ALADDIN
Start date: September 1, 2024
Phase: Phase 3
Study type: Interventional

This is a monocentric, prospective, double-arm, randomized, open-label, implementation-effectiveness hybrid type III study aimed at comparing hospital-based and home-based administration of CAB LA + RPV LA treatment for HIV-1-infected patients. Study participants receiving IM CAB + RPV will complete various questionnaires and scales, including FIM, AIM, IAM, EQ-5D-5L, HAT-QoL, and HIVTSQ, throughout the study. HCPs will also complete FIM, AIM, IAM, and a Likert scale.

NCT ID: NCT06465862 Not yet recruiting - Hiv Clinical Trials

Development of a Silica Microparticle Taggant System to Measure ART Adherence

TruTag
Start date: July 1, 2024
Phase: N/A
Study type: Interventional

Developing technologies to help measure and provide tools to support medication-taking behaviors (medication adherence) is an important step to ending the human immunodeficiency virus (HIV) epidemic. TruTag Technologies has pioneered the use of a microparticle system that can be incorporated into the coating of medications may help users both identify the medication they are taking and record adherence events. By using a standard smartphone camera, shining light on TruTag-coated medications automatically identifies them to an onboard smartphone app which then indirectly records the adherence event. This study evaluates the real-world usability and feasibility of operating this system among people living with HIV (PLWH).

NCT ID: NCT06463886 Not yet recruiting - Hiv Clinical Trials

Striving Towards EmPowerment and Medication Adherence R01

Start date: July 1, 2024
Phase: N/A
Study type: Interventional

This is a study for Black women living with HIV to test a counseling program for Black women living with HIV. This participant may be a good fit if the participant is a Black woman, living with HIV, has a history of trauma, and is currently taking Antiretroviral Therapy (ART) medicines

NCT ID: NCT06451341 Not yet recruiting - HIV Clinical Trials

IMplementation of CAB+RPV LA for People With HIV in Non-Metropolitan Areas

IM-CAPABLE
Start date: June 2024
Phase:
Study type: Observational

The goal of this implementation science study is to learn about the experience of receiving and providing cabotegravir + rilpivirine long-acting (CAB+RPV LA) injections as treatment for human immunodeficiency virus (HIV) for people who live a significant distance from an HIV provider. The main questions it aims to answer are: - Is CAB+RPV LA feasible and acceptable to patients and staff? - What barriers and supports exist and have the most impact on receiving and providing CAB+RPV LA? - How does CAB+RPV LA affect HIV stigma, treatment satisfaction, medication adherence and viral suppression? People living with HIV who reside outside of the Omaha, Nebraska metro area and are starting CAB+RPV LA as part of regular medical care for HIV will be invited to participate in this study by completing questionnaires and an interview over 15 months. Clinic staff who are involved in providing HIV care and CAB+RPV LA will also provide input through questionnaires and an interview.

NCT ID: NCT06449196 Not yet recruiting - HIV Clinical Trials

Mosaic HIV-1 Envelope Trimer Immunogens Administered to People Living With HIV (PLWH) in Africa

C112
Start date: August 1, 2024
Phase: Early Phase 1
Study type: Interventional

An Experimental Medicine Vaccine Trial of Mosaic HIV-1 Envelope Trimer Immunogens Administered to People Living with HIV (PLWH) in Africa, Randomized for Assessment of Fractional Doses.

NCT ID: NCT06444360 Not yet recruiting - HIV Clinical Trials

Behavioral Activation and Risk Reduction for Stimulant Use Among Sexually Active Young Gay/Bisexual Minority Men (IMPACT)

IMPACT
Start date: July 22, 2024
Phase: N/A
Study type: Interventional

The use of behavioral intervention to reduce stimulant use and concurrent HIV sexual transmission risk

NCT ID: NCT06436274 Not yet recruiting - Hiv Clinical Trials

Efficacy of Human Papillomavirus (HPV) Vaccination to Prevent Infection Among Women Living With HIV.

HOPE II
Start date: September 2024
Phase: Phase 4
Study type: Interventional

The Efficacy of Human Papillomavirus (HPV) Vaccination to Prevent Infection Among Women Living with HIV: A Prospective, Individual, Double-Blind, Randomized Controlled Study is evaluating immediate or delayed single-dose nonavalent HPV vaccination among women living with HIV who received one HPV vaccination prior to HIV diagnosis.

NCT ID: NCT06435026 Not yet recruiting - HIV Clinical Trials

Optimizing PrEP Regimens for Pregnant Women in Sub-Saharan Africa (O-PrEP Study) - Stage 1

Start date: May 2024
Phase: Phase 2
Study type: Interventional

This study aims: (1) to determine the optimal dose of emtricitabine/tenofovir disoproxil fumarate (FTC/TDF) for daily oral pre-exposure prophylaxis (PrEP) during pregnancy based on drug pharmacokinetics, and (2) evaluate the maternal and infant safety of increased FTC/TDF doses during these periods.

NCT ID: NCT06432725 Not yet recruiting - Hiv Clinical Trials

Joining Under-connected Networks to Optimize "Salud" (Health) ("JUNTOS")

Start date: July 1, 2024
Phase: N/A
Study type: Interventional

The objective of this study is to evaluate the JUNTOS Referral Network as an implementation strategy to enhance the reach of HIV-prevention and treatment services to Latino gay, bisexual, and other men who have sex with men (MSM).

NCT ID: NCT06428643 Not yet recruiting - Hiv Clinical Trials

A Seek, Test, and Treat Intervention to Reduce Chlamydia Trachomatis Disparities

Start date: September 1, 2024
Phase: N/A
Study type: Interventional

This study includes testing for four STIs (chlamydia, gonorrhea, syphilis, and HIV) at no cost. If positive, individual subjects will also be counseled and offered options for treatment for themselves and their sex partners that may include no cost expedited treatment and the option to be rescreened 3 months after treatment.