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Histology clinical trials

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NCT ID: NCT05843526 Completed - Dental Implants Clinical Trials

Influence of Implant Component Materials on Peri-implant Soft Tissue Horst Response.

PISTI
Start date: May 1, 2019
Phase: N/A
Study type: Interventional

The aim of this study was to characterize the host-related response of peri-implant soft tissue induced by 3 different materials: titanium, resin and PEEK (polyetheretherketone) on man. The primary endpoint is to asses the histological data available: Histological analyses are carried out with immunohistology (CD68, CD3, CD20, macrophages), non decalcified histology to appreciate the structure of the peri implant soft tissues (Sulcus depth, junctional epithelium, connective tissue adhesion). Moreover: scanning electronic microscope (SEM) of the experimental abutment is performed to juge the cell adhesion on the abutment surface. The secondary endpoint is to assess clinical data, radiological bone remodeling regarding the different material. The hypothesis is that resin abutment lead to more inflammation than PEEK or titanium.

NCT ID: NCT04577495 Completed - Thymoma Clinical Trials

Prognostic Factors in Patients Submitted to Surgical Treatment for Thymoma

Start date: January 2005
Phase:
Study type: Observational

Thymoma is the most common primary tumor of the anterior mediastinum. Complete surgical resection is the mainstay of treatment of these tumors. The staging and histological classification of thymoma is still a matter of discussion. Preoperative computed tomography (CT) scan parameters that correlate with histology, stage and prognosis also still have to be completely assessed. The aim of this study is to evaluate the potential association between clinical, radiologic and pathologic characteristics in patients submitted to surgical treatment for thymoma, assessing their prognostic value. Data of patients submitted to surgical resection for pathologically proven thymoma at our Department of Thoracic Surgery between January 2005 and December 2015 will be retrospectively reviewed. The correlation of preoperative CT scan features, histological and pathological characteristics of thymomas will be evaluated, assessing the prognostic role of these factors.

NCT ID: NCT03775811 Completed - Colonoscopy Clinical Trials

In Vivo Computer-aided Prediction of Polyp Histology on White Light Colonoscopy

Start date: January 1, 2019
Phase:
Study type: Observational

Our group, prior to the present study, developed a handcrafted predictive model based on the extraction of surface patterns (textons) with a diagnostic accuracy of over 90%24. This method was validated in a small dataset containing only high-quality images. Artificial intelligence is expected to improve the accuracy of colorectal polyp optical diagnosis. We propose a hybrid approach combining a Deep learning (DL) system with polyp features indicated by clinicians (HybridAI). A pilot in vivo experiment will carried out.

NCT ID: NCT01880021 Completed - Humans Clinical Trials

Synthetic Mesh Explant Study

Start date: March 2008
Phase: N/A
Study type: Observational

The purpose of this study is to determine whether synthetic hernia mesh materials undergo physical and/or chemical changes while in the body.

NCT ID: NCT01642693 Completed - Laser Clinical Trials

Histological Change of The Dentinal-Pulp Complex and Root Resorption

Start date: June 2006
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of the study is evaluate the histological changes of the dentinal-pulp complex and root resorption in maxillary premolars with intrusive orthodontic movement under a low power laser effects.