Hirschsprung Disease Trends

Hirschsprung Disease Clinical Trial

Official title:

Inpatient Care Utilization and Epidemiology of Hirschsprung Disease in the United States: Analysis of the National Inpatient Sample

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05038345
• Other study ID #: 18-697
• Status: Completed
• Start date: March 13, 2019
• Est. completion date: August 15, 2021

Study information

• Verified date: June 2022
• Source: University of New Mexico
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Hirschsprung disease (HD) is associated with significant morbidities including long-term bowel dysfunction. The aim of this study was to update national and regional trends in the epidemiology and inpatient care utilization of HD in the United States between 2009 and 2014 using the National Inpatient Sample (NIS).

Recruitment information / eligibility

• Status: Completed
• Enrollment: 4643
• Est. completion date: August 15, 2021
• Est. primary completion date: August 15, 2021
• Gender: All
• Age group: N/A to 18 Years

Eligibility

Inclusion Criteria:

• We included all patients who were 18 years or younger with an ICD-9-CM code of 751.3 for HD among the first 10 diagnosis.

Exclusion Criteria:

• Data from 2015 to 2018 were not included since diagnoses and procedures were reported using the ICD-10-CM coding system.

Related Conditions & MeSH terms

• Hirschsprung Disease

Intervention

Procedure:
• Pull through surgery
The principal purpose of pull through surgery for Hirschsprung disease is to remove aganglionic bowel and reconstruct the intestinal tract by connecting the normally innervated bowel just above the anus so that normal sphincter function is preserved.

Locations

Country	Name	City	State
United States	University of New Mexico	Albuquerque	New Mexico

Sponsors (1)

Lead Sponsor	Collaborator
University of New Mexico

Country where clinical trial is conducted

United States, 

References & Publications (1)

Huang EY, Tolley EA, Blakely ML, Langham MR. Changes in hospital utilization and management of Hirschsprung disease: analysis using the kids' inpatient database. Ann Surg. 2013 Feb;257(2):371-5. doi: 10.1097/SLA.0b013e31827ee976. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The primary objective of this study was to analyze cost of HD-related admissions in the United States between 2009 and 2014 using the National Inpatient Sample (NIS) database.		2009 to 2014.