Prosthetic Hip Infections: Prospective Study — PHIPS  

Hip Prosthesis Infection Clinical Trial

Official title: Prospective Study of Patients Treated for Prosthetic Hip Infection and Followed for at Least 2 Years

Status Completed

Clinical Trial Summary

Data from large prospective cohort studies of prosthetic joint infections are lacking.

Aim of this study: analyzing prospectively the incidence of reinfection in patients with prosthetic hip infections who underwent surgery and received antibiotic therapy.

Hypothesis: to confirm in a large group that the incidence of reinfection after excision -synovectomy in acute prosthesis hip infection is 30% and 15% for chronic infection after exchange arthroplasty (one or two stage exchange).

Clinical Trial Description

Aim of the study: to analyze the incidence of reinfection in patients with prosthetic hip infection who underwent surgery and received antibiotic therapy Methods: prospective cohort study in a French referral center for osteoarticular infections from November 2002 to March 2010. Population

• all patients who consented to participate in the study with prosthetic hip infections treated by:

• debridement-synovectomy for acute infection or with one-stage or two-stage

• exchange arthroplasty or resection arthroplasty for chronic infection

• antibiotic therapy

Outcome:

• Follow-up: minimum of 2 years

• Events monitored: reinfection including relapse and new infection, joint revision for mechanical reasons, prosthetic hip infection related and non-related deaths ;

Related Conditions & MeSH terms

• Communicable Diseases
• Hip Prosthesis Infection
• Infection

• NCT number: NCT01963520
• Study type: Observational
• Source: Groupe Hospitalier Diaconesses Croix Saint-Simon
• Status: Completed
• Phase: N/A
• Start date: August 2, 2002
• Completion date: September 10, 2015