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Hip Fractures clinical trials

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NCT ID: NCT03519594 Completed - Clinical trials for Multiple Pelvic Fractures

The Size of Pelvic Hematoma Can be a Predictive Factor for Angioembolization

Start date: January 1, 2011
Phase:
Study type: Observational

Unstable pelvic fracture with bleeding can be fatal, with a mortality rate of up to 40%. Therefore, early detection and treatment are important in unstable pelvic trauma. We investigated the early predictive factors for possible embolization in patients with hemodynamically unstable pelvic trauma. The purpose of this study was to predict the necessity of embolization and the timing of angiography using CT scans.

NCT ID: NCT03497949 Completed - Hip Fractures Clinical Trials

Peri-operative Vasopressor Support in Patients Operated for an Acute Hip Fracture (AHF)

Start date: January 20, 2017
Phase:
Study type: Observational

The incidence of hypotension perioperatively during operation of an acute hip fracture is unknown. As a surrogate factor the usage of vasopressor support is more adequate as the registration of vasopressor drugs are many times not complete in records. The investigators retrospectively investigated the anesthetic journals of 1100 patients with an acute hip fracture (AHF) noting confounding factors and the usage of vasopressors either by injections or infusions and then correlated these results to mortality at 30-, 90- and 365- days

NCT ID: NCT03476824 Completed - Pelvic Fracture Clinical Trials

Pelvic Fractures in the Elderly

PelvFx
Start date: January 1, 2006
Phase:
Study type: Observational

The aim of the project is to predict the patient under conservative therapy as a function of the patient Classification of Rommens and Hofmann and other potential prognostic factors. A corresponding prognostic score may be used in the future by patients and attending physicians support joint decision between surgical and conservative treatment.

NCT ID: NCT03475771 Completed - Clinical trials for Venous Thromboembolism

Retrospective Evaluation of Thrombo-embolic Complication in Pelvic Fracture Surgery

Start date: March 24, 2017
Phase:
Study type: Observational

Pelvic fracture are very often treated by surgery ; however there are a high level of thrombotic risk during the surgery (venous thrombo embolic events represent about 10% to 50%. The aim of our study is to report the number of these events and identify the risk factor associated to these events regarding Greenfield Risk Assessment Profile .

NCT ID: NCT03470662 Completed - Delirium Clinical Trials

Prevention of Delirium Among Elderly Patients With Hip Fractures

Start date: March 1, 2017
Phase: N/A
Study type: Interventional

Objective: To evaluate the effect of care bundle on prevention of delirium among elderly patients with hip fractures. Methods: A prospective randomized case control study was performed for 80 patients (≥65 years) with hip fractures treated surgically according to their ages and the type of fractures from March 1th of 2017 to June 30th of 2017.There were 11 males and 69 females, with the age of (79.3±7.84) years. Confusion assessment method (CAM) was applied to diagnose delirium after surgery, the subjects were randomized divided into experimental group (n=43) and control group (n=37). The parameters next were recorded and analyzed, including age, gender, type of fractures, type of internal instrument, amount of bleeding, time between injured to surgery, time length of operation, type of operation, VAS, incidence of delirium, perioperative complications and adverse events.

NCT ID: NCT03468192 Completed - Hip Fractures Clinical Trials

Cluster-randomized Study of 394 Patients Operated With Direct Anterolateral Approach.

Start date: January 1, 2010
Phase: N/A
Study type: Interventional

394 participants were cluster-randomized during 2010-2014. Depending on which ward the participants admitted to, they were allotted to free rehabilitation (non-precaution group, NPG, n=226) or our conventional regime with precautions and mandatory assistive equipment (precaution group, PG, n=168). The participants were followed during hospital stay, at 6 weeks (postal questionnaire), 3 month (visit) and 6 months (reading of medical records) by means of function tests, health-related quality of life (EQ-5D) and other patient-reported outcome measures (PROM).

NCT ID: NCT03451916 Completed - Hip Fracture Clinical Trials

Treatment of Muscle Injury Following Arthroplasty for Hip Fracture (HF)

Start date: July 26, 2018
Phase: Phase 3
Study type: Interventional

The objectives of this study are to assess the efficacy, safety, and tolerability of PLX-PAD intramuscular administration for the treatment of muscle injury following arthroplasty for HF.

NCT ID: NCT03426501 Completed - Hip Fracture Clinical Trials

Association Between HRV and Postoperative Mortality in Hip Fracture Patients

HRVHip
Start date: January 15, 2008
Phase: N/A
Study type: Observational

165 patients admitted to two hospitals were included and short-time HRV measurements were obtained. Mortality data were gathered from the Norwegian central address register. Patients, close relatives of patients and in some cases their general physicians or nursery home physicians were interviewed six months postoperatively regarding the incidence of pneumonia, cardiac events or stroke.

NCT ID: NCT03422497 Completed - Surgery Clinical Trials

The Association of Sex With Guideline-based Perioperative Care in Hip Fracture Surgery

Start date: May 2013
Phase: N/A
Study type: Observational

The investigators will use multilevel multivariable regression analysis to measure the association of sex with provision of guideline-based perioperative care for hip fracture surgery in Ontario.

NCT ID: NCT03401138 Completed - Fracture of Hip Clinical Trials

Hemodynamic Monitoring and Resuscitation in Hip Fractures

Start date: February 14, 2018
Phase:
Study type: Observational

Background: Fracture of the hip is a potentially fatal event in an elderly, frail, highly comorbid patient group suffering from dehydration and hypovolemia, and it carries a risk that equals major trauma in young patients in regard of physiological insult and severity, yet no preoperative resuscitation and transfusion strategy is available. An important goal of hemodynamic monitoring and resuscitation is early detection of insufficient tissue perfusion and oxygenation. The peripheral perfusion index reflects changes in peripheral perfusion and blood volume and a decreased peripheral perfusion index predicts surgical complications and morbidity in acute surgical and septic shock patients. The research group hypothesize that elderly frail patients with a fracture of the hip suffer from hypovolemia and peripheral hypoperfusion of varying degrees and accordingly respond to controlled fluid resuscitation and that the non-invasive peripheral perfusion index will serve as an early predictor of a deteriorated circulation in reflection of stroke volume. Methods: The main objective of this prospective observational study is to assess to what extend patients with fracture of the hip suffer from hypovolemia and respond to a fluid challenge. The secondary objectives are to evaluate correlation between the minimally-invasive measurements of stroke volume and blood volume and the non-invasive measurement of peripheral perfusion index and near-infrared spectroscopy, as well as prevalence of postoperative complications and mortality. Fifty consecutive patients over the age of 65 years, presenting with a hip fracture, treated in a multimodal fast-track regimen, will be included when written informed consent is available. All patients will receive epidural analgesia and preoperative stroke volume-guided hemodynamic optimization. Blood volume measurements are performed and all patients are monitored with peripheral perfusion index and near-infrared spectroscopy. Discussion: This is likely the first study to address clinically applicable hemodynamic monitoring and resuscitation in patients with fracture of the hip where adequate resuscitation is easily missed. The study group aim to evaluate the feasibility of preoperative stroke volume-guided hemodynamic optimization in the context of minimally- and non-invasive monitoring of peripheral perfusion and blood volume measurements.