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Hip Fractures clinical trials

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NCT ID: NCT05749367 Not yet recruiting - Clinical trials for Anesthesia, Conduction

Lateral Cutaneous Nerve and PENG Blocks Versus Suprainguinal Fascia Iliaca Block in Post-op Analgesia of Hip Fractures

Start date: March 6, 2023
Phase: N/A
Study type: Interventional

Postoperative pain in hip fractures is challenging and requires adequate management. Peripheral nerve blocks are already known as superior than systemic analgesia in this scenario, but the best analgesic regional technique is still unknown. The investigators propose a study to compare the postoperative analgesia of hip fractures between pericapsular nerve group block plus lateral femoral cutaneous nerve block and suprainguinal fascia iliaca block

NCT ID: NCT05743179 Recruiting - Pneumonia Clinical Trials

The Effect of Zoledronate on the Prevention of Pneumonia in Hip Fracture Patients

Zoo-P
Start date: December 5, 2022
Phase: Phase 4
Study type: Interventional

Nitrogen-containing bisphosphonates (N-BPs; such as alendronate and zoledronate) are commonly used in the treatment of osteoporosis and fracture prevention, in which zoledronate has a proven better efficacy than alendronate. In 2018, our real-world propensity score matched study showed that the use of N-BPs was significantly associated with reduced risk of myocardial infarction and stroke in hip fracture patients. In addition to cardiovascular diseases, both preclinical study and sensitivity analysis also suggest evidence for N-BPs in pneumonia prevention. Moreover, a pragmatic clinical trial is developed to evaluate effect of the tested intervention in real-life routine clinical practice since traditional explanatory radomised controlled trial (RCT) may have poor generalizability due to highly selected patients and controlled environments. This study aims to evaluate if zoledronate reduces risk of pneumonia in hip fracture patients using pragmatic clinical trial approach. This is an open-label, multi-centre, pragmatic, randomised controlled trial. Patients will be recruited from 4 hospitals, namely Caritas Medical Centre, Prince of Wales Hospital, Queen Mary Hospital, and United Christian Hospital. Age, sex, body mass index, eGFR, history of fracture, chronic respiratory diseases, and other medical history, will be measured and recorded at recruitment.

NCT ID: NCT05721924 Recruiting - Hip Fractures Clinical Trials

Comparing The Effectiveness Of Pericapsular Nerve Group (PENG) Block Versus Supra-Inguinal Fascia Iliaca Compartment Block(S-FICB) In Reducing Positional Pain During Neuraxial Anaesthesia In Hip Fractures Patients

Start date: December 1, 2022
Phase: Phase 4
Study type: Interventional

Fractures in and around the hip are common in the elderly and most of them required early surgical fixation. Hip fractures are accompanied with a considerable amount of pain. Based on National Orthopaedic Registry Malaysia (NORM), spinal/neuraxial anaesthesia makes up 66.3%, is the preferred mode of anaesthesia. Severe pain associated with fractured hip often results in difficulty during positioning for neuraxial anaesthesia and hence it is extremely challenging to position the patients in sitting or lateral position for neuraxial anaesthesia procedures. A supra-inguinal fascia iliaca compartment block (S-FICB), a 3 in 1 block involving femoral nerve , lateral femoral cutaneous nerve and obturator nerve. It is famous technique among anaesthesiologist to treat immediate and postoperative pain in hip fractures patients. The pericapsular nerve group (PENG) block is an ultrasound-guided approach, first described by Giron-Arango et al. in 2018 for the blockade of the articular branches of the femoral, obturator and accessory obturator nerves that provide sensory innervation to the anterior hip capsule. It is an alternative regional anaesthesia technique for the management of acute pain after hip fracture. The goal of this clinical trial is to compare the effectiveness of (PENG) block vs (S-FICB) block in reducing positional pain during neuraxial block in patients going for elective internal fixation of neck of femur fractures. And investigators's hypothesis is PENG block is as effective as S-FICB in reducing positional pain during neuraxial block in patients going for elective internal fixation of neck of femur fractures.

NCT ID: NCT05712850 Enrolling by invitation - Clinical trials for Sacroiliac Joint Dysfunction

Clinical Outcome and Fusion Results Using the SiJoin® Transfixing Sacroiliac Fusion Device

Start date: January 19, 2023
Phase:
Study type: Observational

The purpose of this clinical study is to evaluate fusion of the SI joint(s) and any reduction in VAS pain scores in a prospective cohort of patients utilizing the SiJoin® Transfixing Sacroiliac Fusion Device in patients that received sacroiliac fusion, without ancillary stabilization devices.

NCT ID: NCT05712252 Recruiting - Frailty Clinical Trials

Risk Factors for Fall and Fracture

Start date: February 1, 2023
Phase:
Study type: Observational [Patient Registry]

This project aims to improve the global outcome for an aging individual after a traumatic fall, through identifying conditions contributing to a fall and promoting recovery and rehabilitation. Through better understanding 'falling phenotype', the ultimate aim is to prevent future complications, as well as new falls and fractures in the growing older population.

NCT ID: NCT05697965 Not yet recruiting - Clinical trials for Arthroplasty Complications

LocalVancomycinPowderToPreventPeriprostheticJointInfection.

Start date: March 1, 2023
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and complication profile of local vancomycin application in primary arthroplasty. The investigators hypothesized that the use of local antibiotics would decrease the rate of infection compared to controls and this will be achieved by applying 1 gm of vancomycin powder intracapsularly.

NCT ID: NCT05686278 Recruiting - Hip Fractures Clinical Trials

Observational Study to Evaluate Long-Term Outcome in Hip Hemiarthroplasty

Start date: June 29, 2023
Phase:
Study type: Observational

This PMCF study is designed to collect safety and efficacy data on hip hemiarthroplasty surgeries with Corin BiPolar-i shell and the Oceane+ or Meije Duo femoral stem up to 10 years.

NCT ID: NCT05680714 Active, not recruiting - Hip Fractures Clinical Trials

Does the New Fall- and Fracture Prevention Initiative in Oslo Have Effect?

Start date: January 1, 2012
Phase:
Study type: Observational [Patient Registry]

The goal of this controlled before and after study is to evaluate a new patient pathway for patients 65 years and older who have suffered a fall injury. The main questions the study aims to answer are whether this preventive initiative with improved care coordination reduces risk of subsequent hip fractures, admittance to nursing homes or death. Researchers will compare two boroughs in Oslo who implemented the new patient pathway with the 13 other boroughs who did not reorganize their follow-up, but continued their care as usual.

NCT ID: NCT05678101 Active, not recruiting - Hip Fractures Clinical Trials

TENS for Relief of Postoperative Pain in Orthopedic Patients

Start date: November 1, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

To ensure early mobilization, minimize suffering, and to prevent postoperative complications postoperative pain, should be reduced as soon and as effectively as possible. A non-pharmacological post-operative intervention in terms of the application of transcutaneous electrical nerve stimulation (TENS), could have the potential to accelerate early mobilization and reduce the use of opioids. The overall aim is to demonstrate that the addition of TENS to standard postoperative pain management of orthopedic patients can alleviate pain during mobilization and at rest

NCT ID: NCT05677191 Not yet recruiting - Clinical trials for Trochanteric Fractures

PFNA vs Dual Mobility in Treatment of Unstable Trochanteric Fractures

Start date: January 1, 2023
Phase: Phase 2
Study type: Interventional

Proximal femoral nail [PFNA] versus dual mobility arthroplasty in treatment of unstable trochanteric fractures