High Grade Glioma Clinical Trial
Official title:
Personalized Translational Platform for Biomarker Discovery in Brain Tumors
The central hypothesis for this proposal is that multimodal (clinical, imaging, tissue) biomarkers will better predict early brain tumor response to treatments and will be more reliable prognostic markers in patients with malignant brain tumors.
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Status | Clinical Trial | Phase | |
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Active, not recruiting |
NCT05023551 -
Study of DSP-0390 in Patients With Recurrent High-Grade Glioma
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Early Phase 1 | |
Terminated |
NCT01902771 -
Dendritic Cell Vaccine Therapy With In Situ Maturation in Pediatric Brain Tumors
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Phase 1 | |
Active, not recruiting |
NCT02655601 -
Trial of Newly Diagnosed High Grade Glioma Treated With Concurrent Radiation Therapy, Temozolomide and BMX-001
|
Phase 2 | |
Terminated |
NCT03690869 -
REGN2810 in Pediatric Patients With Relapsed, Refractory Solid, or Central Nervous System (CNS) Tumors and Safety and Efficacy of REGN2810 in Combination With Radiotherapy in Pediatric Patients With Newly Diagnosed or Recurrent Glioma
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Phase 1/Phase 2 | |
Completed |
NCT01466686 -
Low Dose Radiation Therapy for Glioblastoma Multiforme
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Phase 2 | |
Recruiting |
NCT05212272 -
MRI in High-Grade Glioma Patients Undergoing Chemoradiation
|
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Recruiting |
NCT05925218 -
Circulating Tumor DNA Collection From Patients With High Grade Gliomas
|
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Active, not recruiting |
NCT04911621 -
Adjuvant Dendritic Cell Immunotherapy for Pediatric Patients With High-grade Glioma or Diffuse Intrinsic Pontine Glioma
|
Phase 1/Phase 2 | |
Not yet recruiting |
NCT06333899 -
Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion
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Early Phase 1 | |
Recruiting |
NCT04734444 -
SonoClear Acoustic Coupling Fluid (ACF) Mimicking Brain Tissue
|
N/A | |
Completed |
NCT03775369 -
Glioma and Exercising
|
N/A | |
Completed |
NCT02022644 -
Study of Convection-Enhanced, Image-Assisted Delivery of Liposomal-Irinotecan In Recurrent High Grade Glioma
|
Phase 1 | |
Completed |
NCT00780819 -
Borderzone Sampling
|
N/A | |
Recruiting |
NCT06072586 -
Study of BDTX-1535 in Recurrent High-Grade Glioma (HGG) Participants With EGFR Alterations or Fusions
|
Early Phase 1 | |
Completed |
NCT01390948 -
A Study of Bevacizumab (Avastin) in Combination With Temozolomide (TMZ) and Radiotherapy in Paediatric and Adolescent Participants With High-Grade Glioma
|
Phase 2 | |
Recruiting |
NCT03952598 -
Studying the Biology of IDH-mutant Gliomas Via Longitudinal Observation of 2-hydroxyglutarate (2-HG) Using MR Spectroscopy
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N/A | |
Recruiting |
NCT05630664 -
Liquid Biopsy in High-grade Gliomas and Meningiomas
|
||
Recruiting |
NCT05298995 -
GD2-CAR T Cells for Pediatric Brain Tumours
|
Phase 1 | |
Completed |
NCT01222754 -
Lenalidomide and Radiation Therapy in High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas
|
Phase 1 | |
Recruiting |
NCT05278208 -
Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors
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Phase 1/Phase 2 |