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The Factors Causing Treatment Failure in Children Receiving Oxygen Therapy With High-flow Nasal Cannula

Respiratory Distress Clinical Trial

Official title:
Determination of the Factors Causing Treatment Failure in Children Receiving Oxygen Therapy With High-flow Nasal Cannula Due to Moderate and Severe Respiratory Distress

Clinical Trial Summary

The goal of this observational study is to identify the variables that predict treatment failure in order to identify the patients in which HFNC treatment may fail and not delay the transition to advanced respiratory support treatments in these patients. The main questions it aims to answer are: - What factors contribute to the failure of HFNC treatment in these children? - What is the frequency of HFNC treatment failure in children with moderate and severe respiratory distress? Researchers will compare the group whose HFNC treatment was successful with the group whose HFNC treatment failed to identify factors that cause treatment failure.

Clinical Trial Description

Oxygen therapy with a high-flow nasal cannula (HFNC) is a well-tolerated, relatively new, non-invasive alternative ventilation treatment modality. On the other hand, HFNC failure delays advanced respirator supportive treatments, prolongs hospitalization in the intensive care unit, and emergency department, and causes a significant increase in morbidity and mortality with hypoxemia, neurological impairment, and/or hemodynamic instability. The investigators aimed to identify the variables that predict treatment failure in order to identify the patients in which HFNC treatment may fail and not delay the transition to advanced respiratory support treatments in these patients. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06146439
Study type Observational [Patient Registry]
Source Dr. Behcet Uz Children's Hospital
Contact
Status Completed
Phase
Start date October 1, 2018
Completion date February 1, 2020
View Details
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