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Cost-effectiveness of Adalimumab and Surgery vs Adalimumab in HS — HS-COST  

Hidradenitis Suppurativa Clinical Trial

Official title:
Cost-effectiveness of Adalimumab With Adjuvant Surgery Versus Adalimumab Monotherapy in the Treatment of Hidradenitis Suppurativa'

Clinical Trial Summary

The primary objective of this randomized controlled clinical trial in a real life setting is to evaluate the cost-utility of limumab monotherapy compared with the combination of adalimumab and a maximum of three surgeries after two years of treatment in adult patients with moderate to severe HS.

Clinical Trial Description

The primary objective of this randomized controlled clinical trial in a real life setting is to evaluate the cost-utility of limumab monotherapy (Group A) with the combination of adalimumab and a maximum of three surgeries (Group B) years of treatment in adult patients with moderate to severe HS.

Patients in group A will be treated with adalimumab monotherapy according to normal clinical practice and will be given the possibility to crossover into Group B when they do not achieve the HiSCR after 6 months of treatment. Additionally patients will be offered treatment with infliximab, according to clinical practice, until the last surgery. Patients in group B will receive adalimumab combined with a maximum of three adjuvant excisions of active lesions, both according to routine clinical practice. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03221621
Study type Interventional
Source Erasmus Medical Center
Contact Kelsey van Straalen, MD
Phone + 31 107040110
Email k.vanstraalen@eramsusmc.nl
Status Recruiting
Phase Phase 4
Start date July 31, 2018
Completion date July 31, 2022
View Details
See also
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