Clinical Trials Logo
  1. Home
  2. Herniated Disc
  3. NCT01014520

Efficacy of Gabapentin or Amitriptyline to Reduce Postoperative Pain After Lumbar Laminectomy and Diskectomy

Intervertebral Disc Displacement Clinical Trial

Official title:
Comparative Effects of Single Dose Preemptive Gabapentin or Amitriptyline on Postoperative Pain and Opioid Consumption in Single Level Lumbar Laminectomy and Diskectomy: A Double Blind RCT With Placebo Control

Clinical Trial Summary

The hypothesis of this study is that Gabapentin or Amitriptyline has no role in preemptive analgesia to reduce postoperative pain after lumbar diskectomies.

Clinical Trial Description

Pain suppression plays a decisive role in patients' satisfaction following lumbar diskectomies, as the psychological component of the pain is a major cause of treatment failure.

Controversy exists whether preemptive prescription of gabapentin, as a known contributor to reduce postoperative pain, has a role in patients undergoing laminectomy for lumbar diskectomy or spinal canal stenosis.The aim of this study is to test the efficacy of amitriptyline and gabapentin in this group of neurosurgical patients. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01014520
Study type Interventional
Source Tabriz University
Contact Dawood Aghamohammadi, MD
Phone +98 411 3340830
Email daghamohamadi@yahoo.com
Status Recruiting
Phase Phase 2
Start date May 2009
Completion date March 2010
View Details
See also
  Status Clinical Trial Phase
Completed NCT02384928 - Effects of Shinbaro Pharmacopuncture in Sciatic Pain Patients With Lumbar Disc Herniation N/A
Recruiting NCT04538807 - EMG Finding According to the Type of Lumbar Disc Herniation
Terminated NCT00095095 - Lumbar Interbody Fusion Using the Telamon® Peek™ Versus the Telamon® Hydrosorb™ Fusion Device Phase 4
Completed NCT02609854 - Sustained Acoustic Medicine for Chronic Low Back Pain Secondary to Herniated Nucleus Pulposus or Other Conditions N/A
Withdrawn NCT02196883 - Steroid Injections Given at the "Level of MRI Pathology" Versus at the "Level of Clinical Symptoms" to See if One is More Effective Than the Other. N/A
Enrolling by invitation NCT05110833 - Dose Responsiveness as a Measure of Clinical Effectiveness During Neuromonitored Spine Surgery
Completed NCT03750591 - Observational Study on Effectiveness and Safety of Integrative Korean Medicine Treatment for Inpatients With Sciatica Due to Lumbar Intervertebral Disc Herniation
Completed NCT03426215 - Long-Term Course of Korean Medicine Treatment for Lumbar Disc Herniation
Active, not recruiting NCT03959098 - Effectiveness and Safety of Korean Medicine Treatment for Cervical Disc Herniation
Recruiting NCT02936765 - Comparison of Software-assisted Implantation of Elastic Spine Pad (TM) With Respect to Postoperative Change in Neck Disability Index (NDI) With the Conventional Disc Spacer Squale (TM) After Anterior Cervical Discectomy for Cervical Disc Prolapse N/A
Recruiting NCT02936739 - Comparison of Software-assisted Implantation of Elastic Spine Pad (TM) With Respect to Postoperative Change in Neck Disability Index (NDI) With the Conventional Disc Prosthesis Rotaio (TM) After Anterior Cervical Discectomy for Cervical Disc Prolapse N/A
Completed NCT03571503 - The Effectiveness of Doin (Conduction Exercise) of the Pelvic Joint for HLD With Radiating Leg Pain
Completed NCT01922063 - Physiotherapy Following Disc Surgery: Long Term Follow-up of a RCT Phase 3
Enrolling by invitation NCT05098431 - Comparison of Three Approaches of Electrode Placement to Detect Changes in Motor Evoked Potentials During Spine Surgery N/A
Completed NCT05022121 - Integrated Supported Biopsychosocial Self-Management for Back Related Leg Pain N/A
Completed NCT02889484 - Outcome of Surgery for Sciatica - a Comparison of Data From Three National Quality Registries N/A
Completed NCT02351206 - Lumbar Disc Space Height in Young Disc Herniation and Degeneration Patients
Completed NCT05753579 - Is Regression Possible in Lumbal Disc Herniation With Spinal Mobilization Applications? N/A
Completed NCT05804357 - The Effect of Manual Therapy on Psychological Factors and Quality of Life in Lumbal Disc Herniation Patients N/A
Not yet recruiting NCT03011866 - Tranexamic Acid in Reducing Gross Hemorrhage and Transfusions of Spine Surgeries N/A