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Hernia clinical trials

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NCT ID: NCT02439060 Active, not recruiting - Hernia Clinical Trials

PUBMIC (Prophylactic Use of Biologic Mesh in Ileal Conduit)

Start date: November 25, 2015
Phase: N/A
Study type: Interventional

This randomized phase III trial studies how well biologic mesh works in preventing parastomal hernia in patients with bladder cancer who are undergoing radical cystectomy, or removal of the bladder, and ileal conduit diversion. An ileal conduit is a tube created from your small intestine that will be used as a tube for urine to flow out of your body. Parastomal hernia is a type of hernia that can occur in the stomach area where the ileal conduit is placed. Biologic mesh may help prevent parastomal hernia following surgery and ileal conduit diversion.

NCT ID: NCT02419443 Active, not recruiting - Clinical trials for Peripheral Nerve Disorder Associated With Repair of Hernia

The Impact of Perioperative Gabapentin on Chronic Groin Pain After Inguinal Hernia Repair

Start date: August 2011
Phase: Phase 4
Study type: Interventional

A common source of morbidity after IHR is chronic groin pain(CGP), usually defined as pain lasting longer than 3 months. Gabapentin is an anticonvulsant that is also of benefit in the treatment of neuropathic pain. We propose a randomized, double-blind, placebo controlled study of the effect of gabapentin on CGP after IHR. Their pain will be assessed with a visual analogue scale. For those reporting pain, the need for pain medication, or other treatment, and the effect of pain on their quality of life will be recorded.

NCT ID: NCT02372032 Active, not recruiting - Clinical trials for Lumbar Disc Herniation

A Trial of Percutaneous Lumbar Discectomy Combined With Ozone for Treatment of LDH

Start date: February 2015
Phase: Phase 3
Study type: Interventional

Lumbar disc herniation (LDH) is a common pathological process leading to spinal surgery. Open discectomy used to be a widespread procedure for surgical treatment for symptomatic LDH. Currently, several minimal invasive surgeries have been uesd widely. Percutaneous lumbar discectomy(PLD) and ozone therapy are two widely used minimal invasive treatment, and ozone therapy combined other minimally invasive treatment could improve other minimally invasive treatment's clinical effectiveness. The effectiveness of which has been proved to be comparable to conventional open discectomy. In this study, a single-blind randomized controlled trial will be performed to evaluate the effectiveness of two minimal invasive discectomy, percutaneous lumbar discectomy combined with ozone and percutaneous lumbar discectomy, for the treatment of symptomatic LDH. Two groups of patients will be investigated; 1) patients diagnosed with lumbar disc herniation undergoing PLD combined with ozone, and 2) patients diagnosed with lumbar disc herniation undergoing PLD. The primary endpoints of the study will be changes in in pain and functional status by the Visual Analog Scale (VAS) and functional status as measured by Oswestry Low Back Disability Questionnaire (Oswestry Disability Index,ODI) and Japanese Orthopaedic Association (JOA) as measured at pre- and post-operation, 1 month, 3 months, 6 months. Secondary outcomes include response evaluation by MacNab response evaluation criteria as measured at pre- and post-operation, 1 month, 3 months, 6 months. Treatment effect is defined as the difference in the mean change from baseline between the two groups. For the first time,the results of this trial will provide scientific evidence as to the relative effectiveness of PLD combined with ozone versus PLD for minimal invasive surgical treatment for symptomatic lumbar disc herniation.

NCT ID: NCT02365194 Active, not recruiting - Weight Loss Clinical Trials

Modifying Risk in Ventral Hernia Patients

Start date: May 2015
Phase: N/A
Study type: Interventional

A pre-operative physical conditioning and weight loss intervention (prehabilitation) compared to standard counseling prior to ventral hernia repair for obese patients (BMI 30-40 kg/m2) at a safety-net hospital results in a higher proportion of patients being hernia- and complication-free 2 years after surgical consultation.

NCT ID: NCT02363790 Active, not recruiting - Hernia, Ventral Clinical Trials

Primary Fascial Closure With Laparoscopic Ventral Hernia Repair: A Randomized Controlled Trial

Start date: March 2015
Phase: N/A
Study type: Interventional

This study is comparing the outcomes patients undergoing LVHR, PFC as opposed to a bridged repair with assessment of patient reported satisfaction and function at 6 months of follow-up.

NCT ID: NCT02341222 Active, not recruiting - Hernia Clinical Trials

BP as a Super-light Mesh and as a New Fixation Device for General Surgery -DM108/2008-B

DM108/2008-B
Start date: January 2008
Phase: Phase 0
Study type: Interventional

The Buckypaper (BP) is an innovative material that has attracted the attention of many research groups engaged in the study of its possible applications in various technological fields. Our purpose is demonstrate the viability of the application of nanotechnologies to the General Surgery in human with thwe use of a new self standing prosthetic device for the reconstruction of abdominal wall defects.

NCT ID: NCT02328352 Active, not recruiting - Incisional Hernia Clinical Trials

"BP as a New Device for Surgery and Solid Cancer and Hematopoietic System Tumors Treatment. Effects of BP Implantation"

DM159
Start date: October 2010
Phase: Phase 1/Phase 2
Study type: Interventional

Nanotechnologies applied to General Surgery and Emergency Surgery: The Buckypaper as a new fixing method for prosthetic materials in the treatment of abdominal wall hernias in humans, in laparotomic procedures and as a new device for the treatment of solid cancer and hematopoietic system tumors. The experimentation on this new material, preliminary conducted on breed female rabbit New Zeeland, will be applicable to human, if the results in terms of toxicity and durability will be comfortable.

NCT ID: NCT02272322 Active, not recruiting - Cystocele Clinical Trials

Transvaginal Treatment of Symptomatic Cystocele Grade II-III

BCR
Start date: June 2014
Phase: N/A
Study type: Observational

This observational study will evaluate treatment of symptomatic cystocele grade II-III with Cousin Biomesh and Allium Medical Endofast Reliant. Data about 100 patients will be collected. Follow-up till 3 years after the procedure. Primary endpoint is absence of recurrence.

NCT ID: NCT02137018 Active, not recruiting - Incisional Hernia Clinical Trials

"Nanotechnologies Applied to General Surgery and Emergency Surgery: Buckypaper as a New Fixing Method for Prosthetic Materials for the Treatment of Hernia and Incisional Hernia in Laparotomy and Laparoscopic

36P
Start date: March 2013
Phase: Phase 1/Phase 2
Study type: Interventional

"Nanotechnologies applied to General Surgery and Emergency Surgery: The Buckypaper as a new fixing method for prosthetic materials in the treatment of abdominal wall hernias, diaphragmatic hernias, diaphragmatic rupture, incisional hernia and abdominal wall disaster in laparotomy procedure and laparoscopic procedures". Experimentation on breed pig Lantrace ANIMAL MODEL.

NCT ID: NCT02121743 Active, not recruiting - Parastomal Hernia Clinical Trials

Use of a Biological Mesh (StratticeTM) for the Prevention of Parastomal Hernia After Colorectal Surgery With Colostomy

PROBIOCOL
Start date: April 14, 2014
Phase: N/A
Study type: Interventional

In France around 5,000 colostomies are performed after elective or emergency surgery. These colostomies could be associated with major outcomes including parastomal hernia (4 - 53%) of cases. To reduce the incidence of these outcomes, several methods have been proposed but the more pertinent consist in the use of a biological mesh during the stoma's conception. Nevertheless there is no data on the use of a biological mesh (StratticeTM) for the prevention of parastomal hernia.