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Hernia clinical trials

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NCT ID: NCT03613350 Completed - Clinical trials for Lower Urinary Tract Symptom in Severe Cystocele Women

Prevalence Rates of USI, BO, DO and Their Clinical and Urodynamic Findings in Women With ≥Stage II Cystocele

Start date: November 1, 2011
Phase:
Study type: Observational

Prevalence rates of urodynamic stress incontinence (USI), bladder oversensitivity (BO) /detrusor overactivity (DO) or both and their related clinical and urodynamic findings in women with ≥ pelvic organ prolapse quantification stage II cystocele are important for clinical consultation. Thus, the aim of this study was to elucidate the above findings and between-group associations.

NCT ID: NCT03613324 Completed - Clinical trials for Bladder Outlet Obstruction and Detrusor Underactivity in Women With Severe Cystocele

BOO and DU and Their Clinical and Urodynamic Findings in Women With ≥Stage II Cystocele

Start date: January 1, 2011
Phase:
Study type: Observational

Prevalence rates of bladder outlet obstruction (BOO) and detrusor underactivity (DU) and their related clinical and urodynamic findings in women with ≥ pelvic organ prolapse quantification stage II cystocele are important for clinical consultation. Thus, the aim of this study was to elucidate the above findings and between-group associations.

NCT ID: NCT03613311 Completed - Clinical trials for Urodynamic Stress Incontinence in Severe Cystocele Women

Evident, Occult and no Demonstrated USI and UDS Findings in Women With ≥Stage II Cystocele

Start date: November 1, 2011
Phase:
Study type: Observational

Prevalence rates of urodynamic urinary incontinence (USI) subtypes and their related clinical and urodynamic findings in women with ≥ pelvic organ prolapse quantification stage II cystocele are important for clinical consultation, especially for occult USI. Misdiagnosis of occult USI before cystocele repair might lead to occurrence of de novo stress urinary incontinence after cystocele repair. Thus, the aim of this study was to elucidate the above findings and between-group associations.

NCT ID: NCT03607838 Completed - Clinical trials for Lumbar Disc Herniation

SI-6603 (Condoliase) Study for Lumbar Disc Herniation (Discovery 6603 Study)

Start date: May 30, 2018
Phase: Phase 3
Study type: Interventional

This study is to evaluate the effectiveness of a single-dose intervertebral disc injection of SI-6603 in subjects with lumbar disc herniation (LDH)

NCT ID: NCT03591146 Completed - Inguinal Hernia Clinical Trials

Phase I/II Dose-escalation Study to Evaluate Safety, PK and Efficacy of TLC590 for Postsurgical Pain Management

Start date: July 31, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

Phase I/II, randomized, double-blind, comparator-controlled, dose-escalation study to assess the safety, PK, and efficacy of single postsurgical application of TLC590 compared with Naropin®

NCT ID: NCT03576222 Completed - Incisional Hernia Clinical Trials

Preventive PICO on Surgical Wounds After Large Incisional Hernia Repair

PICO
Start date: May 1, 2017
Phase: N/A
Study type: Interventional

To determine the efficacy on decreasing the rate of surgical wound complications in patients undergoing repair of large incisional hernias, after the prophylactic application of a single-use negative pressure therapy dressing (PICO), versus a conventional dressing.

NCT ID: NCT03575377 Completed - Hernia Clinical Trials

Opioid Use, Storage, and Disposal Among Pediatric Patients After Surgery

Start date: June 7, 2018
Phase: N/A
Study type: Interventional

Opioids are an important component of post-operative pain management among children, but are often prescribed in excess and rarely disposed of appropriately. The lack of prompt and proper opioid disposal after recovery from surgery is contributing to the opioid crisis in Ohio by placing children at risk of accidental ingestion of opioids remaining in the home and allowing for unused opioids to be diverted for non-medical use. The investigators propose to reduce the burden of the opioid crisis in Ohio by testing a strategy to increase proper opioid disposal by families of children undergoing outpatient surgery. The investigators will test the impact of a novel opioid disposal mechanism, the Deterra® drug deactivation system, after pediatric surgical operations. This system deactivates pills, liquids, or patches, allowing for their disposal in the home garbage. The investigators propose to evaluate the effectiveness of providing Deterra® bags to families of children having surgery on their disposal of excess opioids. The investigators will perform a randomized controlled trial (RCT) to test the effectiveness of Deterra® to improve opioid disposal among families of children having outpatient surgery at Nationwide Children's Hospital.

NCT ID: NCT03566784 Completed - Inguinal Hernia Clinical Trials

Electrocoagulation Employment During TAPP Inguinal Hernia Repair

Start date: June 1, 2018
Phase:
Study type: Observational

Laparoscopic TAPP (transabdominal preperitoneal) hernia repair presents a minimally invasive surgical procedure, which tends to be a gold standard in a wide range of inguinal hernia operations. Postoperative neuralgia is a troublesome complication following TAPP, which occurs in 0.2-7% of patients. The most common cause of nerve injury is an inappropriate use of electrocoagulation or dangerous tissue dissection during TAPP. However, the association between electrocoagulation employment during TAPP and postoperative neuralgia has not been investigated properly until now. The aim of the project is to compare postoperative pain (postoperative neuralgia) in patients undergoing TAPP inguinal hernia repair with/without the use of electrocoagulation.

NCT ID: NCT03566433 Completed - Inguinal Hernia Clinical Trials

Postoperative Pain After Endoscopic TEP vs. Lichtenstein Hernioplasty in Inguinal Hernia Repair

Start date: November 1, 2017
Phase: N/A
Study type: Interventional

Immediate pain reaction and return to work after TEP or Lichtenstein hernia repair have not been studied. In this multicenter trial the patients are allocated to surgery using TEP (n=50) or Lichtenstein (n=50) technique. Pain and return to work are recorded postoperatively up to one month. Immediate and late complications are also analyzed.

NCT ID: NCT03563092 Completed - Clinical trials for Inguinal Hernia Without Obstruction or Gangrene

Closed Suction Drain vs no Drain on Symptomatic Seroma Formation After Laparoscopic Inguinal Hernia Repair

SALHS
Start date: August 1, 2018
Phase: N/A
Study type: Interventional

The current study aims to determine whether a use of closed suction drain following laparoscopic inguinal hernia surgery performed for an inguinoscrotal variety can decrease the incidence of symptomatic seroma formation requiring interventions and thus, prevent postoperative morbidity.