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Hernia, Inguinal clinical trials

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NCT ID: NCT03918798 Recruiting - Hernia, Inguinal Clinical Trials

The Efficacy and Safety of Chloroprocaine 1% and 2% in Pediatric Population

Start date: February 14, 2019
Phase: Phase 2
Study type: Interventional

Randomized, multi-center, double-blind, two-armed, parallel active groups, prospective trial to evaluate the efficacy and safety of local anesthetic Chloroprocaine at two different concentrations ( at 1% and 2%) in a pediatric population subjected to peripheral nerve block due to Inguinal hernia repair or Flat foot surgery. The present Protocol is part of an extensive Pediatric Investigational Plan (PIP) in the contest of the marketing authorization application of chloroprocaine use for perineural block. The PDCO has adopted a positive opinion.

NCT ID: NCT03904888 Recruiting - Inguinal Hernia Clinical Trials

Conventional Versus Robot Assisted Laparoscopic Inguinal Hernia Repair

Start date: September 23, 2019
Phase: N/A
Study type: Interventional

Evaluate the early postoperative course of patients undergoing laparoscopic inguinal hernia repair with either a conventional or a robot assisted approach and with or without the injection of the trocar wounds with a local anesthetic.

NCT ID: NCT03856710 Recruiting - Inguinal Hernia Clinical Trials

Self Fixating Versus Stapled Mesh for Laparoscopic Inguinal Hernia Repair

Start date: September 22, 2017
Phase: N/A
Study type: Interventional

Inguinal (groin) hernias are common and occur when an internal part of the body pushes through a weakness in the surrounding tissue wall of the groin. They are more likely to occur in men and affect people's quality of life by causing pain that is worse after any strenuous activity. If untreated they can cause serious problems such as strangulation when too much bowel comes through the weakness and becomes squeezed with the risk of losing blood supply requiring emergency surgery. To prevent such complications, elective surgery for symptomatic inguinal hernias is undertaken either in the conventional open method which involves a cut in the groin, or the keyhole surgery, when the surgery is undertaken via three small incisions in the abdomen (instead of a single, larger groin incision), a thin tube containing a light source and a camera (laparoscope) is inserted through one of these incisions, so the surgeon can see inside the abdomen. Special surgical instruments are inserted through the other incisions, so the surgeon can pull or push the hernia back into place and a piece of mesh is then stapled or glued to secure it to the weakened area in the abdomen wall. Securing the mesh with staple has been associated with increased post-operative pain and analgesia requirement; whereas not doing so has been thought to increase the chances of recurrence- more so in large sized weakness. A newer mesh appears to offer benefit over conventional meshes as it grips the tissues around the weakness without requiring staples or glue to fix it in place, and has shown to cause lesser post-operative pain and recurrence. This study is going to compare the newer self-gripping mesh with the conventional mesh requiring fixation to see which is best for patients undergoing keyhole repair to fix inguinal hernias.

NCT ID: NCT03673163 Recruiting - Chronic Pain Clinical Trials

Lidocaine Infusion for Pain After Herniotomy

LIPAH
Start date: November 6, 2018
Phase: N/A
Study type: Interventional

This study seeks to investigate lidocaine infusion to reduce occurrence of chronic postoperative pain at 3-month after inguinal herniotomy

NCT ID: NCT03512366 Recruiting - Local Anaesthesia Clinical Trials

Comparison Between Desarda and Lichtenstein's Technique for Inguinal Hernia Repair Under Local Anaesthesia

Start date: December 9, 2017
Phase: N/A
Study type: Interventional

Inguinal hernia repair is done by two methods. The conventional method uses a prosthetic mesh for strengthening the defect but has been associated with complications. Another new method uses a strip of the external oblique aponeurosis to do the same.There is a necessity to conduct studies comparing the two methods of hernia repair under local anaesthesia in terms of feasibility, economic benefits, faster ambulation with less complications. The purpose of the study is to find a method that will lead to faster disposal of patients and early return to activities, thereby reducing the waiting list of patients that compromises their financial and social spheres and overwhelms the welfare system.

NCT ID: NCT03488342 Recruiting - Clinical trials for Primary Inguinal Hernia

Rives Technique Versus Lichtenstein Repair for Primary Inguinal Hernia

Start date: September 2015
Phase: N/A
Study type: Interventional

Lichtenstein technique, inserting a mesh over the inguinal cord in the neurological plane, is considered the standard of inguinal hernia repair, but it has 4% recurrence and 12% chronic postoperative pain. Rives technique inserts the mesh in the preperitoneal space behind the neurological plane and the muscular plane, thus better fulfilling the principle of hydrostatics.

NCT ID: NCT03355950 Recruiting - Hernia, Inguinal Clinical Trials

ASA Levels in TEP and Lichtenstein Repair Patients

Start date: January 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to determine and compare the possible affects of two different inguinal hernia repair technique (TEP and Lichtenstein) on serum ASA levels.

NCT ID: NCT03262688 Recruiting - Postoperative Pain Clinical Trials

Safety, Tolerability, PK, and Analgesic Effect of INL-001 in Children Following Open Inguinal Hernia Repair

Start date: June 16, 2017
Phase: Phase 3
Study type: Interventional

A multicenter, single-dose study in children 12 to <17 years of age, 6 to <12 years of age, and 2 to <6 years of age who are scheduled for elective open inguinal hernia repair. Enrollment in this study will start with the oldest age group (12 to <17 years) and will continue in a stepwise fashion until appropriate doses are established for all 3 pediatric age groups (12 to <17 years, 6 to <12 years, 2 to <6 years).

NCT ID: NCT03167047 Recruiting - Hernia, Inguinal Clinical Trials

Post-operative Pain Relief for Paediatric Inguinal-Scrotal Surgery

Start date: November 1, 2016
Phase: N/A
Study type: Interventional

Two methods of pain control in children undergoing surgery on the groin and scrotum are caudal injection (a form of epidural) with local anaesthetic, and a regional nerve block (an injection of local anaesthetic around the nerves supplying the area). A pilot study at our hospital showed a significant decrease in post-operative pain and nausea and vomiting in these two methods when compared to intravenous morphine and local anaesthetic to the wound. One potential side effect from caudal injections is temporarily decreased motor power in the legs due to the local anaesthetic - it is thought that this might be overcome using a more dilute solution of local anaesthetic along with clonidine. This study is to demonstrate that this method is as effective as the use of a regional nerve block.

NCT ID: NCT03056027 Recruiting - Inguinal Hernia Clinical Trials

Testicular Vascular Evaluation in Patients Undergoing Inguinal Hernia Repair

Start date: February 2017
Phase: N/A
Study type: Observational

Patients scheduled to undergo laparoscopic preperitoneal or open inguinal hernia repair will be evaluated by means of scrotal/testicular ecocolordoppler ultrasound investigation before and after surgery in order to rule out the potential impact of the surgical procedure on testicular arterial and venous blood flow