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Hernia, Inguinal clinical trials

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NCT ID: NCT02616406 Completed - Hernia, Inguinal Clinical Trials

Objective Measure of Recovery After Outpatient Surgery

Start date: November 2015
Phase:
Study type: Observational

This is a study using wearable monitoring devices, patient activity and sleep patterns to monitor pre and post operative following outpatient inguinal hernia surgery to determine when these parameters return to baseline.

NCT ID: NCT02604732 Recruiting - Inguinal Hernia Clinical Trials

Pre-operative Withdrawal of Aspirin in Laparoscopic Inguinal Hernia Repair

Start date: April 1, 2016
Phase: N/A
Study type: Interventional

This study aims to assess the need to stop Aspirin before elective laparoscopic inguinal hernia repair. It will consist of 2 arms: patients who continue to take Aspirin perioperatively and patients who stop Aspirin 5-7 days before the surgery.

NCT ID: NCT02599623 Recruiting - Anesthesia Clinical Trials

Safety and Efficacy of Local Anesthesia in Emergency Inguinal Hernia Surgery

Start date: January 2016
Phase: N/A
Study type: Interventional

This prospective randomized is designed to evaluate the safety and efficacy of hernia repairs using local anesthesia compared with those using general anesthesia for patients with incarcerated hernia.

NCT ID: NCT02561910 Completed - Clinical trials for Unilateral Inguinal Hernia With Gangrene and Obstruction

Effectivity of Laparoscopic Inguinal Hernia Repair (TAPP) in Daily Clinical Practice - Early and Long-term Results

Start date: January 2000
Phase: N/A
Study type: Observational

The effectiveness of laparoscopic inguinal hernia repair still remains unclear. During a one year period a total of 1208 inguinal hernias in 952 patients were consecutively operated using the laparoscopic technique by a total of 11 general surgeons in daily clinical routine. Laparoscopic hernia repair in the TAPP technique seems to have the potential to become the standard procedure in inguinal hernia repair in future.

NCT ID: NCT02559102 Completed - Clinical trials for Neurodevelopmental Disorder

Dexmedetomidine Sedation Versus General Anaesthesia for Inguinal Hernia Surgery in Infants

DEGA
Start date: July 2015
Phase: Phase 3
Study type: Interventional

This is a prospective randomized controlled trial comparing dexmedetomidine sedation with caudal anaesthesia, and general sevoflurane anaesthesia with caudal anaesthesia for inguinal herniotomies in neonates and infants below 3 months of age. The investigators will compare the efficacy and adverse events associated with each of these techniques and neurodevelopmental outcomes of the infants in each group at 6 months and 2 years of age.

NCT ID: NCT02545270 Completed - Hernia, Inguinal Clinical Trials

Validation of a Subjective Rating Scale for Assessment of the Surgical Workspace in Laparoscopy

Start date: March 2016
Phase: N/A
Study type: Interventional

It is of great importance to obtain optimal surgical conditions for the surgeon in order to increase patient safety. The effect of different interventions on surgical conditions has been assessed by various surgeon-assessed rating scales. A 5-point surgical rating scale has previously been tested in a proof-of-concept trial - but not validated - during radical retropubic prostatectomy by asking different surgeons to evaluate the surgical workspace using video sequences. In an ongoing study (The Hernia Study, Trial registration NCT02247466) performed by investigators group, investigators are using a 5-point scale to rate the surgical workspace during laparoscopic ventral herniotomy with or without neuromuscular blockade. This scale is based on previously used scales by already published studies and has a description connected to each point. To the authors' knowledge the scale has never been validated in a laparoscopic setting, where the intra-abdominal pressure during pneumoperitoneum can have a great influence on visualization. In fact, to investigators knowledge, no validated surgeon-assessed rating scale regarding the surgical workspace during laparoscopic surgery does exists. Purpose: Primary aim: To validate a 5-point rating scale by investigating the inter-rater agreement of evaluations of the surgical workspace at different intra-abdominal pressures. Using intra-abdominal video recordings. Secondary aims: To validate a 10-point rating scale by investigating the inter-rater agreement of evaluations of the surgical workspace at different intra-abdominal pressures. To test the agreement between the two rating scales. To assess which of the two rating scales has the highest inter-rater agreement To assess the intra-rater agreement of both rating scales. Hypothesis: Investigators hypothesize that the 5-point rating scale has an intra-class correlation coefficient (ICC) > 0.6., validated by video-sequences obtained during laparoscopic surgery.

NCT ID: NCT02537860 Completed - Clinical trials for Inguinal Hernia Repair

Paravertebral Block for Inguinal Hernia Repair in Elderly

Start date: December 2015
Phase: N/A
Study type: Interventional

This prospective double-blinded clinical trial is intended to compare three nerve stimulator- guided paravertebral block injections versus five injections for elderly patients undergoing hernia repair regarding intraoperative hemodynamic stability and postoperative pain.

NCT ID: NCT02521831 Withdrawn - Inguinal Hernia Clinical Trials

Neuroinflammatory and Neurocognitive Effects of Spinal vs. Inhalational Anesthesia for Elective Surgery in Infants

Start date: October 2015
Phase: Phase 3
Study type: Interventional

Significant concern regarding the safety of general anesthesia in children has arisen due to myriad animal studies suggesting neurotoxicity of commonly used anesthetic agents. Inflammation of the central nervous system after anesthesia may have a significant role in the pathogenesis of anesthetic-induced neural injury. To evaluate this hypothesis, the investigators propose to randomize healthy infants undergoing elective surgery to one of two anesthetics: 1) spinal anesthesia only; or 2) general inhalational anesthesia with isoflurane, laryngeal mask airway (LMA) or endotracheal tube (ETT), and single-shot caudal block. Primary endpoint will be serum inflammatory biomarkers and transcriptome analysis and secondary endpoint will be neurocognitive outcome at 6 months and 1 year.

NCT ID: NCT02507830 Recruiting - Inguinal Hernia Clinical Trials

Mesh Fixation With a Synthetic Glue in Primary Inguinal Hernia Repair

Start date: August 2015
Phase: N/A
Study type: Observational

Prospective observational study with mesh fixation using FDA approved synthetic glue,glubran 2 and standard mesh fixation with stiches in primary inguinal hernia repair surgery. The investigators aim is to recruit 150 patients for the study. The outcomes The investigators would like to determine are : postoperative pain,recurrences and complication rates such as seromas.

NCT ID: NCT02500056 Completed - Clinical trials for Inguinal Hernia Repair

Single-centre Single-blinded Randomised Study Evaluating the Impact of Mesh Pore Size on Chronic Pain After Lichtenstein Hernioplasty

Start date: January 2011
Phase: N/A
Study type: Interventional

The aim of the present study is to determine whether usage of mesh with larger pores, compared with mesh with smaller pores, would result in decreased rate of chronic pain after open inguinal hernia repair. The patients are randomized into two study gropus receiving mesh with different pore size. Clinical follow-up examination will be performed 1 week, 1 month, 6 months and 3 years after the operation.