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Hernia, Inguinal clinical trials

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NCT ID: NCT03247985 Completed - Hernia, Inguinal Clinical Trials

Tacking Mesh Versus Self-fixating Mesh for Inguinal Hernia Repair

Start date: June 2013
Phase: N/A
Study type: Interventional

Investigators are testing whether tacking mesh or self-fixating mesh used for inguinal hernia repair makes any difference in short-term pain or return to normal activities following the operation. Other studies have shown no significant difference in hernia recurrence rate when metal tacks are not used to hold the mesh in place.

NCT ID: NCT03221686 Completed - Inguinal Hernia Clinical Trials

Effects of Oral Supplementation of Arginine, Zinc and Vitamin C on Collagen Synthesis in Inguinal Hernia Patients

Start date: February 20, 2016
Phase: N/A
Study type: Interventional

Collagen synthesis is depressed systemically in the immediate postoperative period. Arginine, zinc and vitamin C impact collagen synthesis. The aim of this study is to investigate the effect of a pre and postoperative oral supplement consisting of arginine, zinc and vitamin C on collagen synthesis in patients undergoing inguinal hernia repair.

NCT ID: NCT03203343 Completed - Surgery Clinical Trials

Inflammatory Stress Response in Pediatric Inguinal Hernia Repair

Start date: May 1, 2017
Phase: N/A
Study type: Interventional

Today there are various surgical techniques for inguinal hernia. In this study, investigators want to compare the ''PIRS'' operating technique laparoscopy and modified "Marcy" operating technique with open inguinal access. Investigators would compare both groups to find out witch one does the lesser inflammatory stress response on the organism.

NCT ID: NCT03193723 Completed - Inguinal Hernia Clinical Trials

Ultrasound Guided Local Anesthetic Field Block (A Five Step Procedure) for Open Inguinal Hernia Repair

Start date: October 1, 2016
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate success, efficacy, feasibility and safety of a simple five step ultrasound guided local anesthetic infiltration technique for unilateral open inguinal hernia repair and to determine the non-inferiority of the block to spinal anesthesia by comparing intraoperative and postoperative complications, pain control and patient and surgeon satisfaction of the block with spinal anesthesia.

NCT ID: NCT03185637 Completed - Inguinal Hernia Clinical Trials

Children's Surgery in Sub-Saharan Africa

PaedSurgAfrica
Start date: October 1, 2016
Phase: N/A
Study type: Observational [Patient Registry]

Background: Five billion people worldwide do not have access to safe, affordable surgical care. A significant proportion live in sub-Saharan Africa (SSA), where up to 50% of the population are children. There is limited literature on neonatal and paediatric surgery in SSA and children's surgery does not appear on any of the National Health Strategic Plans for the 47 independent countries across SSA. Objectives: To form a collaboration of surgeons and allied health professionals involved in children's surgery across SSA and collectively undertake the largest prospective cohort study of paediatric surgery in this region. Materials and Methods: Data will be collected via REDCap website on all patients with gastroschisis, anorectal malformation, appendicitis, inguinal hernia and intussusception, during a 1-month period of collaborators choice between October 2016 to April 2017, with a 30-day follow up until the end of May 2017. Estimated study population: 1450 patients from 50 institutions. Full ethical approval has been granted by the host centre; local ethical approval will be required at collaborating centres for participation. All collaborators will be co-authors. Primary outcome will be in-hospital all-cause mortality. Secondary outcomes will include post-intervention complications. Data will be collected on institutional facilities, patient demographics, duration from condition onset to presentation, peri-operative resuscitation, intervention and outcome. Differences in outcomes between SSA and benchmark data from high-income countries will be calculated using chi-squared analysis. Multi-level multivariate logistic regression analysis will be used to identify interventions and peri-operative factors associated with improved outcomes; p<0.05 will be deemed significant. Outcome: Results will be used to advocate for enhanced children's surgical services in SSA. We shall identify context-appropriate interventions associated with improved outcome. The collaboration will help to enhance research capacity in the region.

NCT ID: NCT03167047 Recruiting - Hernia, Inguinal Clinical Trials

Post-operative Pain Relief for Paediatric Inguinal-Scrotal Surgery

Start date: November 1, 2016
Phase: N/A
Study type: Interventional

Two methods of pain control in children undergoing surgery on the groin and scrotum are caudal injection (a form of epidural) with local anaesthetic, and a regional nerve block (an injection of local anaesthetic around the nerves supplying the area). A pilot study at our hospital showed a significant decrease in post-operative pain and nausea and vomiting in these two methods when compared to intravenous morphine and local anaesthetic to the wound. One potential side effect from caudal injections is temporarily decreased motor power in the legs due to the local anaesthetic - it is thought that this might be overcome using a more dilute solution of local anaesthetic along with clonidine. This study is to demonstrate that this method is as effective as the use of a regional nerve block.

NCT ID: NCT03155230 Completed - Chronic Pain Clinical Trials

Nationwide Results on Chronic Pain After Bilateral Transabdominal Preperitoneal Inguinal Hernia Repair (TAPP)

Start date: January 1, 2015
Phase:
Study type: Observational

Danish male patients who had undergone bilateral TAPP (July 2012 to June 2013) were recruited from the Danish Hernia Database and cross-checked with hospital files and the National Patient Registry. A standardized postal questionnaire was sent out two years after the index surgery to investigate Patients Related Outcome Measures (PROMs) such as chronic post-operative pain.

NCT ID: NCT03133533 Withdrawn - Hernia, Inguinal Clinical Trials

Laparoscopic Versus Robot-assisted Inguinal Hernia Repair: A Single Institution Randomized Controlled Trial

Start date: May 2018
Phase: N/A
Study type: Interventional

Randomized trial to compare outcomes of laparoscopic and robot assisted inguinal hernia repair.

NCT ID: NCT03128216 Not yet recruiting - Inguinal Hernia Clinical Trials

Local Anesthetic Infiltration VS Trasversalis Fascia Block VS Spinal Anesthesia

Start date: April 2017
Phase: N/A
Study type: Interventional

Propose to comparison effectiveness of blind local anesthetic infiltration with ultrasound guided Transversals Fascia Block and Spinal Anesthesia in patients undergoing to inguinal hernia repair surgery. The effectiveness is defined as pain control during intraoperative and time need to reach hospital discharge criteria in the post-operative period.

NCT ID: NCT03126084 Completed - Postoperative Pain Clinical Trials

Postoperative Effects of TAP Block Versus QLB Type 2 Block

Start date: May 2, 2017
Phase: Phase 4
Study type: Interventional

This study compares analgesic effectiveness of transversus abdominis plane block and quadratus lumborum block type 2 in open hernia repair surgery. All of the patients will receive routine intravenous analgesic regimen. In addition to that one-third of the patients will receive transversus abdominis plane block, one-third will receive quadratus lumborum block type 2. One-third of the patients will not receive any blocks and will constitute the control group