Hereditary Breast and Ovarian Cancer Syndrome Clinical Trial
Official title:
Cohort Study on Characters and Distribution of Inherited Susceptible Genes Among Epithelial Ovarian Cancer Patients and Their Relatives in the North of China
Purpose: To investigate the prevalence of the germline mutations in the BRCA 1/2 and mismatch
repair genes in patients with epithelial ovarian cancer (EOC) and their relatives, and
related somatic mutations in tumor tissues in the northern part of china.
Patients and methods: A multicenter prospective study will be hold in the northern part of
china form 2017. About 1000 female patients with epithelial ovarian cancer and their
ralatives will be tested for germline mutations in the BRCA 1/2 and mismatch repair genes and
related somatic mutations in tumor tissues, regardless of the family history.
Study type: Observational Official title: Prevalence study of germline mutations in
susceptibility ovarian cancer genes in patients with epithelial ovarian cancer and somatic
mutations in their tumor tissures in the northern part of china.
Enrollment: 1000
n/a
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