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Clinical Trial Summary

Iron deficiency is one of the most common nutritional problems observed in patients with obesity and after bariatric surgery. From a therapeutic point of view, iron deficiency can lead to iron deficiency anemia. Iron supplementation carries the risk of exacerbating infections, altering the gut microbiome and iron overload. Therefore, it would be beneficial to use iron supplementation only in truly iron deficient patients. To date, different studies have observed that hepcidin could be a possible indicator of iron status and absorption in different patient populations. Furthermore, it could be used to distinguish anemia due to iron deficiency from inflammation and globin disorder related anemia. How hepcidin concentrations variate in patients with obesity and after bariatric surgery remains unsure.


Clinical Trial Description

During the visit in the obesity clinic, eligible patients will be approached for participation by the sub-investigator. Interested patients will receive information regarding the study and receive the information sheet containing the informed consent form. After signing the informed consent form, general information will be collected regarding medical and demographic data using a short questionnaire. Additional questionnaires regarding demographics and menstrual cycle will be collected. Anthropometric measurements will be collected for the determination of the length, weight, hip circumference, waist circumference and body composition. Finally, blood samples will be collected for the determination of iron and inflammation related markers. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03990948
Study type Observational
Source Universitaire Ziekenhuizen KU Leuven
Contact Nele Steenackers, MSc
Phone 0032 016 34 49 13
Email nele.steenackers@kuleuven.be
Status Recruiting
Phase
Start date January 8, 2019
Completion date December 31, 2023

See also
  Status Clinical Trial Phase
Withdrawn NCT03073369 - Effect of Ergocalciferol on Iron Metabolism in Individuals With Chronic Kidney Disease Phase 4