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Direct Acting Antiviral Therapy in Donor HCV-positive to Recipient HCV-negative Kidney Transplant

Hepatitis C Clinical Trial

Official title:
Pan-genotypic Direct Acting Antiviral Therapy in Donor HCV-positive to Recipient HCV-negative Kidney Transplant

Clinical Trial Summary

This is a proof of concept, single center study for the donation of HCV-positive kidney to HCV negative recipient patients, with preemptive, interventional treatment with 12 weeks of commercially available DAA therapy to prevent HCV transmission upon transplantation.

Clinical Trial Description

The goal of this study is to determine if preoperative dosing and sustained administration of pan-genotypic DAA therapy after kidney transplantation prevents the transmission of hepatitis C virus (HCV) infection from an HCV positive donor kidney to an HCV naïve recipient. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03623568
Study type Interventional
Source Massachusetts General Hospital
Contact
Status Withdrawn
Phase Phase 4
Start date February 15, 2019
Completion date April 15, 2021
View Details
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