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Hepatitis C (HCV) Cure and Kidney Health

Hepatitis C Clinical Trial

Official title:
HCV Cure and Kidney Health: A Prospective, Observational Cohort Study of HCV Genotype 1 and 4 Infected Adults With and Without HIV Infection

Clinical Trial Summary

The purpose of this study is to learn how 12 weeks of HCV treatment with elbasvir and grazoprevir (brand name Zepatier) impacts your kidney function.

Clinical Trial Description

Prospective data collection of 25 Genotype 1 or 4 HCV-infected women from the San Francisco Women's Interagency HIV Study (WIHS) site and 25 Genotype 1 or 4 HCV-infected men from the San Francisco VA Medical Center who are initiated on Zepatier for 12 weeks (Total n=50). For women and men with HCV genotype 1a infection, only those without baseline NS5A resistance mutations will be included. Blood/urine samples will be collected before initiation of treatment, 4 weeks after treatment initiation, 12 weeks after treatment initiation (end of treatment), 24 weeks after treatment initiation to determine Sustained Virological Response (SVR), and at 48 weeks after treatment initiation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03407703
Study type Observational
Source San Francisco Veterans Affairs Medical Center
Contact Phyllis C Tien, MD
Phone 415-221-4810
Email phyllis.tien@ucsf.edu
Status Recruiting
Phase
Start date March 27, 2018
Completion date December 31, 2019
View Details
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