Hepatitis B Clinical Trial
Official title:
Incidence of Hepatitis B Diagnosis Among Diabetes Mellitus Patients of 0-80 Years of Age, in the United Kingdom Clinical Practice Research Datalink (CPRD)
This study is being conducted to assess the risk of hepatitis B (HepB) diagnosis among diabetes mellitus (DM) and non-DM patients of 0-80 years of age with in a large population-based cohort in United Kingdom (UK) using data from the CPRD database.
The study is a retrospective, observational, descriptive, cohort study, in DM and non-DM
patients of 0-80 years of age. As a first step the eligible baseline population from CPRD
will be defined as per the data quality qualifiers, which include subjects aged 0-80 years,
"acceptable for research" registered in practices classified as "up to standard" by the CPRD
for the time period 2000- 2012. The following cohorts will be defined from the baseline
population:
- DM cohort: Patients diagnosed with type 1 or type 2 DM, as confirmed by diagnosis
medical codes with or without a DM related drug or monitoring devices prescription.
- Non-DM cohort: Patients with the absence of personal history of DM diagnosis or
antidiabetic drug or monitoring devices prescriptions.
From the above defined cohorts, HepB cases will be identified based on clinical diagnosis
codes, Hospital Episodes Statistics (HES) or positive diagnostic laboratory tests results.
;
Observational Model: Cohort, Time Perspective: Retrospective
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