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Hepatic Cirrhosis clinical trials

View clinical trials related to Hepatic Cirrhosis.

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NCT ID: NCT06355479 Completed - Hepatic Cirrhosis Clinical Trials

A Study to Evaluate the Efficacy and Safety of OsrHSA in Patients of Hepatic Cirrhosis With Hypoalbuminemia

Start date: April 10, 2023
Phase: Phase 3
Study type: Interventional

The goal of this clinical trial is to evaluate the efficacy of OsrHSA works to treat hypoalbuminemia in hepatic cirrhosis patients. It will also learn about the safety and immunogenicity of OsrHSA. The main question it aims to answer is whether OsrHSA is effective in elevating the serum albumin level of cirrhotic patients with hypoalbuminemia. Researchers will compare OsrHSA to the positive comparator, plasma-derived HSA (pHSA) to see if OsrHSA presents as non-inferior to pHSA in the indication of hypoalbuminemia in hepatic cirrhosis patients. Participants will be randomized in a 1:1 ratio to receive OsrHSA or HpHSA (20g IV qd) for up to 14 days, following an EOT visit. Follow-up visits will be taken on EOT+7d, EOT+14d, and EOT+30d, respectively.

NCT ID: NCT03804593 Completed - Clinical trials for Hepatocellular Carcinoma

HCCBloodTest for Detection of Hepatocellular Carcinoma (HCC)

Start date: December 17, 2018
Phase:
Study type: Observational

This is a multi-center study to prospectively gather clinically-characterized plasma samples to determine the diagnostic performance characteristics (sensitivity and specificity) of the HCCBloodTest among patients with cirrhosis with and without HCC

NCT ID: NCT03712280 Completed - Hepatic Cirrhosis Clinical Trials

MNK6106 for Liver Disease (Hepatic Cirrhosis) That in the Past Has Affected the Brain (Hepatic Encephalopathy)

Start date: December 1, 2018
Phase: Phase 2
Study type: Interventional

The main reason for this study is to see how the study drug interacts with the body. It will compare different doses of the study drug with a drug already in use. Participants will be adults with liver disease that has affected the brain in the past.

NCT ID: NCT03486912 Completed - Liver Fibrosis Clinical Trials

A Study of Experimental Medication BMS-986036 in Adults With Nonalcoholic Steatohepatitis (NASH) and Liver Cirrhosis

FALCON 2
Start date: June 12, 2018
Phase: Phase 2
Study type: Interventional

This is a study of experimental medication BMS-986036 given to adults with Nonalcoholic Steatohepatitis (NASH; the buildup of fat and inflammation in the liver that is not caused by alcohol) and liver cirrhosis (liver damage characterized by normal liver tissue being replaced by scar tissue).

NCT ID: NCT03445208 Completed - Liver Fibrosis Clinical Trials

A Study of Experimental Medication BMS-986036 Given to Healthy Participants

Start date: February 14, 2018
Phase: Phase 1
Study type: Interventional

This is a study of experimental medication BMS-986036 given to healthy participants.

NCT ID: NCT03420768 Completed - Liver Fibrosis Clinical Trials

A Study of Experimental Medication BMS-986263 in Adults With Advanced Hepatic Fibrosis After Cure of Hepatitis C

Start date: February 14, 2018
Phase: Phase 2
Study type: Interventional

This is a study of experimental medication BMS-986263 in adult patients with advanced hepatic fibrosis (scar tissue in the liver caused by inflammation that is far on in progress) after the patient is cured of hepatitis C (an infection caused by a virus that attacks the liver and leads to inflammation).

NCT ID: NCT02778425 Completed - Portal Hypertension Clinical Trials

The Treatment of Hepatocirrhosis and Portal Hypertension

Start date: February 2016
Phase: N/A
Study type: Interventional

This study compare the efficiency of partial splenic embolization +endoscopical therapy with endoscopical therapy alone in gastroesophageal variceal haemorrhage accompanied with splenomegaly or hypersplenism of hepatocirrhosis and portal hypertension treatment.

NCT ID: NCT02230683 Completed - Liver Cirrhosis Clinical Trials

A Study of IDN-6556 in Cirrhotic Subjects With Portal Hypertension

PH
Start date: August 2014
Phase: Phase 2
Study type: Interventional

This is an open-label pilot study to evaluate the safety, tolerability, and efficacy of IDN-6556 in treating portal hypertension in subjects with liver cirrhosis.

NCT ID: NCT02230670 Completed - Liver Cirrhosis Clinical Trials

A Study of IDN-6556 in Subjects With Liver Cirrhosis

LC
Start date: August 2014
Phase: Phase 2
Study type: Interventional

This is a multicenter study to see if treatment with IDN-6556 can help improve the liver function of patients with liver cirrhosis with Model for End-Stage Liver Disease scores between 11-18.

NCT ID: NCT02163512 Completed - Hepatic Cirrhosis Clinical Trials

Effect of Beta-adrenergic Blockers on Cardiac Function, Systemic and Splanchnic Haemodynamic and Kidney Function in Cirrhotic Patiets With Refractory Ascites

ALB-BET
Start date: March 12, 2014
Phase:
Study type: Observational

Multicentric, observational and prospective study with two groups of treatment: Refractory ascites and non-refractory ascites. All patients should be prescribed beta-adrenergic blockers as primary or secondary profilaxis for variceal bleeding.