Hemostatic Disorders Clinical Trial
Official title:
Indicación de transfusión de Hemoderivados en el Postoperatorio de cirugía Cardiaca Tras la implantación de un Sistema de monitorización de la coagulación a la Cabecera Del Paciente: Tromboelastometría Versus Protocolo Habitual de transfusión
Main objective:
Determine whether by introducing thromboelastograph, the investigators reduced the number of
packed red cells received by each patient (median) compared to the usual protocol, in which
the indication for transfusion is based on laboratory tests: Prothrombin time, time
activated partial thromboplastin time, thrombin, reptilase, fibrinogen and platelet contage.
Design:
Prospective randomized controlled trial and single blinded.
Disease or disorder under study:
Study of coagulopathy in patients undergoing cardiac surgery with cardiopulmonary bypass
(CPB).
Primary endpoint:
median transfusion of packed red blood cells per patient. Study population Male and female
patients over 18 years undergoing cardiac surgery with cardiopulmonary bypass to bleed
excessively.
Duration of treatment:
The coagulation monitoring methods tested are made from protamine administration to CEC
output if a) the patient bleeds diffusely, or b) from arrival in the unit if not satisfied
critics a) bleed excessively drains and until the patient stops bleeding (debit drains <a
150ml / h).
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Prevention
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