Clinical Trials Logo
  1. Home
  2. Hemorrhoids
  3. NCT00328900
  4. Details
NCT00328900 Clinical Trial

Measurement of Stress During Anesthesia With "Pain Detector" on Patients Receiving Atropine

Hemorrhoids Clinical Trial

Clinical Trial Details — Status: Unknown status

Administrative data
NCT number NCT00328900
Other study ID # S-03113
Secondary ID
Status Unknown status
Phase N/A
First received May 22, 2006
Last updated May 31, 2012
Start date January 2006

Study information
Verified date April 2007
Source Rikshospitalet University Hospital
Contact Hanne Storm, PhD
Phone +47 23074398
Email hanne.storm@medisin.uio.no
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

24 patients randomly divided into two groups, one of the groups receiving atropine in addition to the planned anaesthesia. Skin conductance parameters to be compared between the two groups.

Description:

Skin conductance (SC), in terms of numbers of skin conduction fluctuations (NSCF), amplitude and mean skin conductance level, reflect the activity in the sympathetic postganglionic cholinergic fibers which innervate the palmar and plantar sweat glands. Skin conductance, especially numbers of skin conductance fluctuations, may be a promising tool to monitor anesthesia. Atropine, an anticholinergic agent, acts as an antagonist on the muscarinic receptors of the sweat glands and inhibits their secretion in a dose-dependent way. The aim of this study was to find out to what degree SC is influenced by i.v. administration of atropine.

Study hypothesis: SC is not influenced by i.v. administration of atropine.

Recruitment information / eligibility
Status Unknown status
Enrollment 24
Est. completion date
Est. primary completion date
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria:

- Patients in ASA-group 1-2

- Operations (anal fissures, anal fistulas and haemorrhoids) lasting for less than one hour

- informed consent

- BMI <30

Exclusion Criteria:

- Patients using any medication known to influence the autonomous nervous system

- Patients with contraindications to atropine (e.i. fibrillation, glaucoma ect)

- BMI >30

- Pregnancy

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Administration of 0,7 mg of atropine

Device:
• Measurement of skin conductance with Pain detector

Locations
Country Name City State
Norway Ulleval University Hospital Oslo

Sponsors (1)
Lead Sponsor Collaborator
Rikshospitalet University Hospital

Country where clinical trial is conducted

Norway, 

Outcome
Type Measure Description Time frame Safety issue
Primary Number of skin conductance fluctuations
See also
  Status Clinical Trial Phase
Completed NCT06216223 - Laser Versus Surgery in Anal Diseases in Inflammatory Bowel Patients N/A
Withdrawn NCT02851940 - Pain and Bleeding Following Hypertonic Saline Sclerotherapy Compared to Brand Ligation for Symptomatic Hemorrhoids N/A
Recruiting NCT02301052 - Evaluation of Allium Ampeloprasum Spp.Iranicum Cream Effect for the Management of Hemorrhoids Symptoms Phase 1/Phase 2
Completed NCT02216305 - HAL-RAR Versus Hemorrhoidectomy in the Treatment of Grade III-IV Hemorrhoids. Prospective, Randomized Trial N/A
Completed NCT02358174 - Hemorrhoids and Metalloproteinases, Observational Study N/A
Completed NCT01483833 - Efficacy Study of Iferanserin to Treat Hemorrhoids Phase 2
Completed NCT00397137 - Stapled Anopexy Versus Closed Haemorrhoidectomy for Haemorrhoids N/A
Completed NCT00841620 - Symptom Control 1-year After Circular Stapler Anopexy or Diathermy Excision for Prolapsed Haemorhoids Phase 4
Completed NCT04276298 - Topical Analgesia Post-Haemorrhoidectomy Phase 2/Phase 3
Completed NCT04675177 - Polidocanol Foam VS Artery Ligation in Hemorrhoidal Disease Phase 2/Phase 3
Recruiting NCT05889962 - Ultrasound-guided Pudendal Nerve Block for Pain After Hemorrhoidectomy N/A
Recruiting NCT01961739 - Topical 2% Lidocaine for the Treatment of Symptomatic Hemorrhoids Phase 2/Phase 3
Active, not recruiting NCT02061176 - THD Versus Open Haemorrhoidectomy N/A
Withdrawn NCT00512044 - Local Versus General Anaesthesia in Stapled Hemorrhoidectomy Phase 4
Completed NCT04031131 - The Use of Topical Anaesthetic in the Banding of Internal Haemorrhoids Phase 2
Recruiting NCT04329364 - RCT Comparing Conventional Haemorrhoidectomy With Laser Haemorrhoidoplasty Phase 2/Phase 3
Completed NCT04567485 - Impact of Moderate to Severe Pain in the Post-intervention Monitoring Room After Hemorrhoidectomy on the Length of Stay in the Outpatient Surgery Unit
Completed NCT05247333 - Implementation of a Minor Ailment Service in Community Pharmacy Practice N/A
Completed NCT03298997 - Ligation and Hemorrhoidopexy Technique Versus Ligation of Hemorrhoidal Arteries Using Ultrasound for Hemorrhoids N/A
Completed NCT05605080 - Hemostatic and Analgesic Effect of Gel Foam and Gauze With Bosmin After Anal Surgery N/A