A Correlation Study of Internal Jugular Vein Variability Under Deep Inhalation and Propofol-induced Hypotension

Hemodynamic Clinical Trial

Official title:

A Correlation Study of Internal Jugular Vein Variability Under Deep Inhalation and Propofol-induced Hypotension

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT06112769
• Other study ID #: 2023-KY-603
• Status: Recruiting
• Start date: October 29, 2023
• Est. completion date: June 2025

Study information

• Verified date: November 2023
• Source: Affiliated Hospital of Jiaxing University
• Contact: Qinghe Zhou
• Phone: 13732573379
• Email: jxxmxy[@]163.com
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

The correlation between internal jugular vein variability during deep inhalation and the decrease in blood pressure during propofol induction.

Description:

1. Ultrasound records at least one quiet breathing cycle and one deep inhalation cycle to calculate IJVV 2. Propofol was infused target-controlled at 4 μg/ml, and changes in arterial blood pressure within 3 minutes of propofol induction were observed. 3. Aim to conduct a prospective observational study to evaluate the correlation between internal jugular vein variability during deep inhalation and the decrease in blood pressure during propofol induction.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 90
• Est. completion date: June 2025
• Est. primary completion date: June 2025
• Accepts healthy volunteers: No
• Gender: All
• Age group: 60 Years and older

Eligibility

Inclusion Criteria:

• age over 60 years
• American Society of Anesthesiology (ASA) status ?-?
• Surgery with radial artery puncture
• Propofol induction

Exclusion Criteria:

• BMI=30kg/m2
• People with short necks;
• Previous hypotension (systolic blood pressure <90mmHg or mean arterial pressure <65mmHg)
• Previous poorly controlled hypertension
• Cardiac insufficiency , EF value<50%
• Upper limb deep vein thrombosis
• History of radiotherapy or neck surgery
• Inability to maintain a supine position for necessary measurements
• Mechanical ventilation status or inability to take deep breaths patients
• gastrointestinal surgery
• patients allergic to propofol.

Related Conditions & MeSH terms

• Hemodynamic
• Hypotension

Locations

Country	Name	City	State
China	Affiliated Hospital of Jiaxing University	Jiaxing	Zhejiang

Sponsors (1)

Lead Sponsor	Collaborator
Affiliated Hospital of Jiaxing University

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	IJVV during deep inhalation	IJVV (%) = (diamax - diamin)/[(diamax + diamin)/2] × 100	1 year