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Hemodynamic clinical trials

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NCT ID: NCT06112769 Recruiting - Hemodynamic Clinical Trials

A Correlation Study of Internal Jugular Vein Variability Under Deep Inhalation and Propofol-induced Hypotension

Start date: October 29, 2023
Phase:
Study type: Observational [Patient Registry]

The correlation between internal jugular vein variability during deep inhalation and the decrease in blood pressure during propofol induction.

NCT ID: NCT05803330 Completed - Hemodynamic Clinical Trials

Study of Alpha-blockers Alone During Preoperative Preparation in Patients With Pheochromocytoma

Start date: February 20, 2014
Phase: N/A
Study type: Interventional

Study of the relationship between hemodynamic stability and preoperative intravenous rehydration in patients with pheochromocytoma

NCT ID: NCT04659642 Recruiting - Hemodynamic Clinical Trials

Attenuation of Airway and Cardiovascular Responses to Extubation in Chronic Smokers

Start date: November 30, 2020
Phase: Early Phase 1
Study type: Interventional

The aim of this blind comparative study was to compare the effects of dexmedetomidine, fentanyl and their combination on airway reflexes and hemodynamic responses to tracheal extubation in Adult chronic male smoking patients scheduled for abdominal surgeries (of average 2-3 hours duration).

NCT ID: NCT03775876 Completed - Sedation Clinical Trials

Dexmedetomidine Versus Propofol in Conjunction With Regional Block for Shoulder Arthroscopy

Start date: March 1, 2017
Phase: Phase 4
Study type: Interventional

Operative shoulder arthroscopy under regional block anesthesia often presents with hemodynamic challenges for the anesthesiologist, knowing that a low systolic blood pressure is required to minimize the bleeding. Regional anesthesia is successfully performed to many patients in whom tracheal intubation or the placement of a laryngeal tube is undesired. Propofol has traditionally been used to provide sedation in patients undergoing shoulder arthroscopy under regional anesthesia. In contrast to Propofol, Dexmedetomidine is a highly selective α-2 adrenoceptor agonist that has been shown to provide sedation, analgesia and anxiolytic effects with minimal respiratory depression. Due to the effect of both drugs on blood pressure, the investigators set out to compare intraoperative hemodynamics of both drugs, along with the surgeon's satisfaction and the degree of comfort provided to patients undergoing interscalene brachial plexus block for shoulder arthroscopy. The investigators also assessed whether the type of anesthetic agent used for sedation accounted for other differences in intra and post-operative outcome measures.

NCT ID: NCT03437148 Terminated - Cardiac Output Clinical Trials

Non-Invasive Shunt Quantification in Interatrial Communication

NISQIC
Start date: July 18, 2018
Phase: N/A
Study type: Interventional

Shunt quantification in atrial septal defect (ASD) is estimated by Echocardiography-Doppler, with the pulmonary-to-systemic blood flow ratio: Qp/Qs. Higher is the ratio, more important is the shunt, and the consequence on right ventricular function. A value higher than 1.5 is one of the criteria for percutaneous closure of Secundum ASD. Maatouk and al. have demonstrated that a shunt fraction (Qp/Qs) over 3 is a predictive factor of an incomplete reversibility of the right ventricular remodeling [1]. Even if the accuracy of Doppler echocardiography is admitted for Qp/Qs measurement, there is still some technical difficulties. Thus, the right cardiac catheterization for O2 consumption measurement by the direct Fick method is used. The major inconvenient is the potential risk of adverse effects. Non-invasive methods have been developed using physical properties (as the thoracic bioimpedance) or inert gas rebreathing technique. Thoracic Bioimpedance (TB) and inert gas rebreathing (IGR) techniques have been studies on healthy individual and different respiratory or cardiac diseases to evaluate the cardiac output (CO). TB and IGR measure the systemic and pulmonary blood flow respectively. Without shunt the pulmonary blood flow is equal to the systemic blood flow. Thus, Investigator suppose that combine the two techniques in disease with shunt, will allow a quantification of the shunt fraction Qp/Qs as accurate as with the gold standard technique (Fick method and Echocardiography Doppler). The purpose of the study is to evaluate the feasibility and the accuracy of the non-invasive measurement of the Qp/Qs ratio in secundum ASD using the IGR technique and the TB versus the two gold standard techniques: the Fick method and the Echocardiography-Doppler. The study hypothesizes that the values of Qp et Qs determined by IGR et TB respectively are in the same range of values that the one determined by gold standard techniques.

NCT ID: NCT03080636 Completed - Exercise Clinical Trials

Sex and Exercise-mode Differences in Post Exercise Blood Pressure and Heart Rate Variability Responses During Workday

Start date: January 1, 2014
Phase: N/A
Study type: Interventional

The present study compared the acute effects of Sex and exercise mode on subsequent blood pressure (BP) and heart rate variability (HRV) responses during daily work in healthy adults. All subjects did 3 sessions: aerobic exercise on a treadmill, resistance exercise at the gym and a seated control session.