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Hemodynamic Response clinical trials

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NCT ID: NCT05238506 Completed - Acute Appendicitis Clinical Trials

Lidocaine VS Hemodynamic, Metabolic and Hormonal Response

Start date: March 12, 2022
Phase: Phase 4
Study type: Interventional

Intravenous lidocaine - a potent local anesthetic with analgesic and anti- inflammatory properties has been shown to be an effective adjunct that reduces intra and postoperative opioid consumption and facilitates pain management in adults. In children population promising but limited evidence is available. The study has been planned to evaluate the efficacy of continuous intravenous infusion of lidocaine in alleviation of hemodynamic reaction to tracheal intubation, as well as metabolic and hormonal response to laparoscopic procedure in children.

NCT ID: NCT03540147 Terminated - Exercise Training Clinical Trials

The Impact of Blood Flow Restriction (BFR) on Exercise and Hemodynamic Responses

Start date: January 26, 2018
Phase: N/A
Study type: Interventional

The impact of blood flow restriction (BFR) on exercise and hemodynamic responses will be studied. The use of BFR will be studied during yoga and low-intensity aerobic exercise in healthy subjects with no history of chronic illness ranging from 18-40 years of age. This study will evaluate several conditions related to cardiovascular physiology in order to determine the safety and efficacy of this type of exercise training. First, the effects of two distinct types of BFR cuffs (BStrong and Hokanson) will be studied during low-intensity aerobic exercise on vascular function. Second, the effect of yoga will be studied with and without the use of BStrong bands on vascular function. Outcome measures include acute effects on endothelial function i.e. flow-mediated dilation, arterial stiffness, beat-by-beat blood pressure, heart rate, RPE (rate of perceived exertion), and blood lactate. For this intervention, the BFR cuffs will be used during exercise to evaluate its safety and efficacy. Since BFR is becoming a widely popular method of exercise, it is important to study its safety and hemodynamic effects.

NCT ID: NCT03077503 Completed - Clinical trials for Hemodynamic Response

Comparison of Dexmedetomidine and Fentanyl to Prevent Hemodynamic Response to Skull Pins Application

Start date: September 1, 2015
Phase: Phase 4
Study type: Interventional

To compare the effect between dexmedetomidine and fentanyl for controlling the hemodynamic response to skull pins application

NCT ID: NCT01238718 Completed - Clinical trials for Hemodynamic Response

Use of Lidocaine in Rapid Sequence Induction

Start date: October 2008
Phase: N/A
Study type: Interventional

Lidocaine has been shown to blunt the cardiovascular response to endotracheal intubation. The incidence of hypertension, tachycardia and dysrhythmias due to laryngoscopy may be increased in patients that receive rapid sequence induction and intubation, where opioids are spared and intravenous anesthetic agents are not titrated step by step. Our hypothesis was that lidocaine when administered intravenously in patients who undergo rapid sequence induction may not only blunt the hemodynamic response to intubation, but may also increase the anesthetic depth (as assessed by BIS), thus further reducing the possibility of hypertension, arrhythmias and also awareness.