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Hemodialysis clinical trials

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NCT ID: NCT05631782 Completed - Hemodialysis Clinical Trials

Effects of Shenkang Decoction on Creatinine and Blood Urea Nitrogen in Chronic Renal Failure Hemodialysis Patients

Start date: November 10, 2020
Phase: Early Phase 1
Study type: Interventional

To explore the clinical effect of Shenkang Decoction in chronic renal failure (CRF) patients with hemodialysis (HD).

NCT ID: NCT05575193 Completed - Hemodialysis Clinical Trials

Acupressure on Uremic Pruritus and Sleep Quality Among Patients Receiving Hemodialysis

Start date: March 15, 2021
Phase: N/A
Study type: Interventional

The research is to explore the effect of acupressure on uremic pruritus and sleep quality among patients receiving hemodialysis. The research method adopts the experimental research method using randomization. The patients receiving the intervention of acupressure are in the experimental group, while those who do not receive it are in the control group.

NCT ID: NCT05552482 Completed - Hemodialysis Clinical Trials

Identifying Risk Factors (RF) for Early Haemodialysis Arteriovenous Fistula Failure (eAVFF)

eAVFF-RF
Start date: January 5, 2021
Phase:
Study type: Observational

Arteriovenous fisutla (AVF) is the vascular access of choice for hemodialysis but has a high early failure (eAVFF) rate. eAVFF can be defined as thrombosis/stenosis and Doppler ultrasound (DUS)-based failure-to-mature parameters such as postoperative blood flow (PostQa) < 500 ml/min, AVF-vein diameter (PostVD) < 5 mm, and AVF-vein depth (PostVDepth) ≥ 6 mm. We explored whether common risk factors for eAVFF could predict these eAVFF parameters and venous distensibility: the latter is largely overlooked as a potential eAVFF parameter.

NCT ID: NCT05535114 Completed - Hemodialysis Clinical Trials

Intradialytic Yoga-resistance Exercise for Hemodialysis Patients

Start date: July 13, 2023
Phase: N/A
Study type: Interventional

Objective: Intra-dialytic exercises are strongly believed to have benefits and have become a crucial therapeutic modality for managing hemodialysis patients. The effects of each type of exercise and yoga on hemodialysis patients' physical and psychological health have been studied extensively. However, the effects of combining yoga and resistance training exercises remain unclear in this population. The aims of this study are: (1) to create a feasible intradialytic yoga-resistance exercise (YRE) program for hemodialysis patients; and (2) to investigate its effects on muscle strength, fatigue, depression, and sleep quality in hemodialysis patients. Methods: Seventy-two participants will be randomly assigned to a 12-week YRE group or a wait-list control group. The YRE group will perform exercises (breathing exercises, flexibility, resistance exercises, relaxation with meditation) in the first two hours of each hemodialysis session, three times weekly. The outcome measures are the following: socio-demographic characteristics; fatigue (measured by the Functional Assessment of Chronic Illness Therapy-Fatigue); depression (the Patient Health Questionnaire); sleep quality (Pittsburgh Sleep Quality Index); muscle strength (a hydraulic hand dynamometer, hand-held dynamometer, and one-minute sit-to-stand test). The outcomes will be assessed at baseline, week 6, and week 12. The independent t-test will be applied to compare the differences in outcome scores between groups at different time points. Using a generalized estimating equation method to analyze the effects of the intervention on the outcome variables. Results: The expected results are: (1) The combined YRE program is feasible and safe for hemodialysis patients. (2) After 12 weeks, the intervention group will show significant improvement in muscle strength, fatigue, depression, and sleep quality compared to the control group.

NCT ID: NCT05533008 Completed - Hemodialysis Clinical Trials

CR845-100303: Study to Assess the Potential of Physical Withdrawal From Intravenous CR845 (Difelikefalin) in Hemodialysis Patients

Start date: December 31, 2019
Phase: Phase 1
Study type: Interventional

This is a multicenter, randomized, double-blind, placebo-controlled study to assess the potential of physical withdrawal from CR845 upon treatment discontinuation after 3 weeks of IV administration at a dose of 0.5 mcg/kg in hemodialysis patients. The purpose of this study is to determine whether hemodialysis patients who take CR845 develop physical dependence and experience withdrawal symptoms upon cessation, as exemplified by symptoms consistent with opioid withdrawal. The study will consist of a Screening Phase, a 3-week Open-label Phase, a 2-week randomized, placebo-controlled, Double-blind Phase and a Follow-up Visit.

NCT ID: NCT05419258 Completed - Hemodialysis Clinical Trials

Feasibility and Evaluation Study of the UPLUG Hemodialysis Connection Device

UPLUG-SAFE
Start date: May 6, 2022
Phase: N/A
Study type: Interventional

The new Uplug° technology, interface between the end of the hemodialysis catheter and the dialysis circuit, makes it possible to limit direct access to the hemodialysis catheter during connections and disconnections. Aim: The investigators propose a feasibility study, in order to study the new Uplug° technology in real conditions of use. Material and methods: This study aim to include 15 hemodialysis patients in a center on a tunneled permanent central venous hemodialysis catheter. The Uplug° technology will be placed at the end of each patient's hemodialysis catheter for a period of one month. Hypothesis tested: The main endpoint is the proportion of hemodialysis sessions performed successfully with this technology, respecting the usual dialysis prescription.

NCT ID: NCT05399199 Completed - Hemodialysis Clinical Trials

Virtual Reality Distraction During Arteriovenous Fistula Puncture

Start date: June 5, 2022
Phase: N/A
Study type: Interventional

The cannulation of arteriovenous fistula is a painful procedure in hemodialysis patients. Previous studies have shown the effectiveness of virtual reality in reducing pain during needle-related procedures

NCT ID: NCT05339711 Completed - Hemodialysis Clinical Trials

Effects of Robotic Cat and Betta Fish Therapies in Hemodialysis Patients

Pet Therapy
Start date: May 1, 2021
Phase: N/A
Study type: Interventional

The research was carried out as a randomized controlled trial to examine the physiological and psychological effects of robotic cat and Betta fish therapies in hemodialysis patients.

NCT ID: NCT05296018 Completed - Hemodialysis Clinical Trials

The Effect of Mandala on Coping With Fatigue, Psychological Well-Being and Stress in Patients Treated With Hemodialysis

Start date: April 4, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to examine the effect of mandala on coping with fatigue, psychological well-being and stress in patients treated with hemodialysis

NCT ID: NCT05274399 Completed - Hemodialysis Clinical Trials

Hopelessness and Self-care Power in Hemodialysis Patients

Start date: February 14, 2020
Phase:
Study type: Observational

The purpose of this study is to investigate the correlation between hopelessness level and self-care agency in patient receiving hemodialysis treatment.