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Hemodialysis Fistula Thrombosis clinical trials

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NCT ID: NCT05906550 Recruiting - Clinical trials for Hemodialysis Access Failure

Flow Dysfunction of Hemodialysis Vascular Access

FLOW
Start date: November 1, 2021
Phase: N/A
Study type: Interventional

The FLOW trial evaluates the follow-up of the vascular access for hemodialysis. In current clinical care, vascular access flow volume is periodically assessed to detect and treat asymptomatic stenosis. The FLOW trial will determine whether it is safe to abandon this practice of active surveillance. Vascular access stenosis will then be treated only when clinical problems of flow dysfunction occur during hemodialysis. The investigators expect that the intervention rate and medical costs will be reduced by 40% when correction of vascular access stenosis is triggered by clinically apparent access dysfunction rather than asymptomatic flow reduction.

NCT ID: NCT05165797 Recruiting - Platelet Activation Clinical Trials

Platelet Activation Affecting the Rate of Vascular Access Patency

Start date: January 1, 2021
Phase:
Study type: Observational

In the case of cardiovascular diseases such as coronary artery disease, cerebrovascular disease, and peripheral arterial disease, there are many studies that the use of antiplatelet agents is very helpful in improving the vascular patency rate, but there are not many studies on the use of antiplatelet agents in the dialysis approach. The basis for use is insufficient. There is a lack of research on whether maintaining a state in which platelet activation is suppressed is helpful in improving dialysis access patency. Therefore, we conducted this study to determine whether the degree of platelet activation affects the patency of vascular access.

NCT ID: NCT03289520 Completed - Kidney Failure Clinical Trials

Clopidogrel Prevention of Early Arteriovenous (AV) Fistula Thrombosis

FISTULA
Start date: January 7, 2003
Phase: Phase 3
Study type: Interventional

The objective of the study is to determine whether clopidogrel reduces the early failure rate of native AV fistulae. This study was originally registered as NCT00067119 which included two protocols, this one and the GRAFT study)

NCT ID: NCT02374762 Completed - Clinical trials for Chronic Kidney Disease

Hemodialysis Vascular Access Imaging Study

Start date: March 2015
Phase: N/A
Study type: Observational

The goal of this study is to find the best techniques to take non-invasive images of the arteriovenous fistula (AVF) in hemodialysis patients.

NCT ID: NCT00737620 Completed - Clinical trials for Hemodialysis Fistula Thrombosis

Evaluation of Heparin Bonded Vascular Graft Versus Standard Graft in Prosthetic Arteriovenous Access for Hemodialysis

Start date: March 2008
Phase: Phase 4
Study type: Interventional

The majority of bridge graft fistula with polytetrafluoroethylene (PTFE) for hemodialysis access will develop stenosis at the venous anastomosis and eventually will fail. Aspirin have been used for many years as a prophylactic drug therapy to prevent thrombosis but good clinical evidence for its benefit is lacking. Many drugs have been used to reduce intimal hyperplasia in animal models. Until recently there has been little success in clinical trials of anti-inflammatory, antiproliferative, antiplatelet, antithrombotic or calcium channel blocking drugs. Recently a major breakthrough was done by GORE when introducing the new heparin bonded PTFE graft by covalent attachment. This trial is planed to assess and compare between the GORE-TEX® PROPATEN vascular graft versus unmodified ePTFE grafts the patency and complication.