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Hemispatial Neglect clinical trials

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NCT ID: NCT01965951 Completed - Stroke Clinical Trials

Remediation of Spatial Neglect Trial

RESPONSE
Start date: July 2013
Phase: N/A
Study type: Interventional

Problems with attention are a common and debilitating consequence of brain injury. Studies show that poor attention is the number one predictor of poor cognitive functioning one year post-injury. This is due to the fact that attention is a necessary component of more complex cognitive functions such as learning & memory, multi-tasking and problem solving. In many cases, individuals may exhibit problems with spatial attention known as 'hemi-spatial neglect syndrome' or simply 'neglect'. Many studies now show that the processing machinery of the brain is plastic and remodeled throughout life by learning and experience, enabling the strengthening of cognitive skills or abilities. Research has shown that brief, daily computerized cognitive training that is sufficiently challenging, goal-directed and adaptive enables intact brain structures to restore balance in attention and compensate for disruptions in cognitive functioning. The study aims to understand how our computer program can affect cognition and attention in those with acquired brain injury.

NCT ID: NCT01735877 Completed - Hemispatial Neglect Clinical Trials

Effectiveness of Mirror Therapy in Stroke Patients With Unilateral Neglect - A Randomized Controlled Trial

MUST
Start date: January 2011
Phase: Phase 3
Study type: Interventional

Hemi spatial neglect, or the tendency to ignore stimuli originating in a portion of the environment contra lateral to a cerebral lesion, can be a major source of functional handicap after stroke. The currently available treatments for unilateral neglect are scanning training, visual cuing approaches, limb activation strategies, visual imagery, tactile stimulation, prisms and sustained attention training.Mirror therapy improves the hand function in sub-acute stroke. Hypothesis: To evaluate the effectiveness of Mirror therapy in the management of stroke patients with unilateral neglect.

NCT ID: NCT01641432 Completed - Stroke Clinical Trials

Computerized Attention Training for Individuals With Acquired Brain Injury

Start date: July 2011
Phase: Phase 1
Study type: Interventional

Problems with attention are a common and debilitating consequence of brain injury. Studies show that poor attention is the number one predictor of poor cognitive functioning one year post-injury. This is due to the fact that attention is a necessary component of more complex cognitive functions such as learning & memory, multi-tasking and problem solving. In many cases, individuals may exhibit problems with spatial attention known as 'hemi-spatial neglect syndrome' or simply 'neglect'. Many studies now show that the processing machinery of the brain is plastic and remodeled throughout life by learning and experience, enabling the strengthening of cognitive skills or abilities. The investigators own research has shown that brief, daily computerized cognitive training that is sufficiently challenging, goal-directed and adaptive enables intact brain structures to restore balance in attention and compensate for disruptions in cognitive functioning.

NCT ID: NCT00955253 Completed - Stroke Clinical Trials

Guanfacine for the Treatment of Spatial Neglect and Impaired Vigilance

GASNIV
Start date: April 2010
Phase: Phase 2
Study type: Interventional

To find out if spatial neglect following stroke and brain injury can be reduced using guanfacine, a drug that was shown to improve neglect in two stroke patients in a previous pilot study (Malhotra et al, 2006). In this trial, the effects of guanfacine will be examined in a larger number of patients, and there will also be a systematic assessment of whether the drug is only effective in patients with particular patterns of brain damage.

NCT ID: NCT00663338 Completed - Hemispatial Neglect Clinical Trials

Dopamine Agonist for Hemispatial Neglect and Motor Deficit Post Stroke

Start date: January 2010
Phase: Phase 2
Study type: Interventional

The aim of this study is to assess the effect of the drug rotigotine on the syndrome of hemispatial neglect and motor deficits following strokes affecting the right hemisphere of the brain.

NCT ID: NCT00271388 Completed - Stroke Clinical Trials

Vestibular Stimulation to Treat Hemispatial Neglect

Start date: January 2006
Phase: N/A
Study type: Interventional

The purpose of the current proposal is to pilot a new and potentially improved treatment for neglect. The procedure involves the delivery of transcutaneous small-amplitude current to the vestibular nerves that lie directly below the mastoid bones.