Clinical Trials Logo
  1. Home
  2. Hemifacial Spasm
  3. NCT01726725

Hemifacial Spasm and Desflurane — HFS  

Hemifacial Spasm Clinical Trial

Official title:
Investigating the Etiology of Hemifacial Spasm (HFS): The Role of Desflurane

Clinical Trial Summary

Patients are chosen to participate in this study because they will undergo a particular type of brain surgery to treat their hemifacial spasm. This surgery is called microvascular decompression (MVD) and involves the facial nerve. The facial nerve is being compressed by one or more blood vessels and this contact produces the facial twitches. The investigators do not know why a blood vessel that touches the facial nerve produces facial twitches. The investigators are interested in investigating this during your surgery. A total of 25 participants are expected to participate in this study.

Clinical Trial Description

"Intra Operative Monitoring" (IOM) is a standard and routine medical practice for patients having MVD surgery. IOM is done to make sure that the hearing and face nerves are not accidentally bumped or damaged during surgery. After anesthetic induction, the neurophysiologist places electrodes for the nerves, on the scalp and muscles. Stimulation and monitoring of muscle twitches are all common, safe and painless medical procedures.

In this study, the investigators would like to measure the nerve and muscle function on the normal side and compare it to nerve and muscle function on the abnormal side during different levels of the anesthetic desflurane. In order to monitor the normal side of the face one additional set of electrodes will be placed in the facial muscles. The investigators will compare responses to three different levels of anesthetic. The technique used will be motor evoked potentials. The effect of the anesthesia on the lateral spread response will also be examined. This response is evident only on the symptomatic side. These observations will take approximately 10 to 15 minutes and will not delay or lengthen the surgery. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01726725
Study type Observational
Source University of Manitoba
Contact
Status Unknown status
Phase N/A
Start date November 2012
Completion date December 2013
View Details
See also
  Status Clinical Trial Phase
Not yet recruiting NCT04474977 - Microvascular Decompressive Surgery for Hemifacial Spasm
Withdrawn NCT01932255 - CSF Leak Following Microvascular Decompression: the Benefit of Routine Postoperative Lumbar Tap N/A
Completed NCT00210431 - Post Marketing Surveillance Study of Dysport
Recruiting NCT03306940 - Botulinum Toxin A in the Treatment of Hemifacial Spasm N/A
Completed NCT05103202 - Efficacy and Safety of 10-Week or Shorter vs 12-Week or Longer Injection Intervals of Botulinum Toxin
Not yet recruiting NCT06195241 - Effects of DaxibotulinumtoxinA for Blepharospasm and Hemifacial Spasm Phase 4
Completed NCT01598961 - Determination of Target of Adequate Partial Neuromuscular Blockade for Electrophysiologic Monitoring During Microvascular Decompression Surgery N/A
Not yet recruiting NCT04589364 - Study of Abobotulinum Toxin Versus Neubotulinum Toxin Injection For Hemifacial Spasm in Thai Patients Phase 3
Completed NCT01613781 - Determination of Target of Adequate Partial Neuromuscular Blockade for Electrophysiologic Monitoring During Microvascular Decompression Surgery N/A
Completed NCT03508882 - Pretarsal Versus Preseptal Botulinum Toxin for Patients With Eyelid Spasm Phase 4
Enrolling by invitation NCT01271634 - Observe Abnormal Potential From the Offending Vessel to the Facial Muscles of HFS Patients N/A
Recruiting NCT04645277 - Magnetic Resonance Imaging Study on Patients With Hemifacial Spasm
Completed NCT03390803 - Effect of Hemifacial Spasm on Intraocular Pressure Measurement N/A
Completed NCT01728428 - A Multicenter, Observational Study to Evaluate Clinical Manifestation, Diagnosis and Treatment of Primary Hemifacial Spasm in Chinese Patients N/A
Completed NCT04621578 - Transcutaneous Electrical Acupoint Stimulation on Postoperative Dizziness in Hemifacial Spasm Patients N/A
Completed NCT00276315 - Assessment of Effectiveness and Safety of Dysport® for the Treatment of Hemifacial Spasm Phase 3
Completed NCT02761096 - Effect of Acupuncture on Inflammation and Immune Function After Craniotomy N/A
Unknown status NCT01564979 - Effect on Tear Functions of Pretarsal and Preseptal Techniques of Botulinum Toxin Type A Injection in Hemifacial Spasm Phase 2
Not yet recruiting NCT01546805 - Testing the Effect of Zinc Supplementation to Improve the Treatment Effect of Botulinum Toxin for Oculofacial Spasm N/A
Completed NCT01168388 - Movement Disorder Survey in East China N/A