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Prospective Clinical Trial for Children With TCRαβ Depleted vs Traditional Haplo Identicle HSCT

Hematopoietic Stem Cell Transplantation Clinical Trial

Official title:
TCRαβ+ Cell Deleted Versus Traditional Haploidentical Hematopoietic Stem Cell Transplantation ：A Single-center, Prospective, Non-randomized Controlled Clinical Study

Clinical Trial Summary

This is a single-center prospective, non-randomized controlled clinical study in China using CliniMACS TCRα/β+ cell depleted stem cell haploidentical donors versus conventional Beijing protocol for haploidentical hematopoietic stem cell transplantation in children.

Clinical Trial Description

1:1 non-randomized controlled clinical study in single center using CliniMACS TCRα/β+ cell depleted stem cell versus conventional Beijing protocol for haploidentical hematopoietic stem cell transplant. The purpose of this study is to obtain 30% decrease grade II-IV aGVHD and better qulity of life for TCRα/β+ cell depleted haploidentical stem cell transplantaion. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06423131
Study type Interventional
Source Shanghai Jiao Tong University School of Medicine
Contact Jing Chen, PhD
Phone 38626161
Email chenjing@scmc.com.cn
Status Recruiting
Phase N/A
Start date May 26, 2024
Completion date March 31, 2028
View Details
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