Hematologic Malignancies Clinical Trial
Official title:
A Phase I Study of Reduced Intensity, Sequential Double Umbilical Cord Blood Transplantation Using ProHema Modulated Umbilical Cord Blood Units in Subjects With Hematological Malignancies.
The purpose of this research study is to determine the safety and efficacy of a reduced intensity conditioning regimen during a double umbilical cord blood unit transplant with one of the cord blood units modulated with ProHema.
The purpose of this research study is to determine the safety and efficacy of a reduced
intensity conditioning regimen during a double umbilical cord blood unit transplant with one
of the cord blood units modulated with ProHema.
-As part of this research study cord units will be modulated in the laboratory with ProHema
before it is given to the participant. Two different treatment groups will be tested. Group
1: will have the second cord blood unit modulated with ProHema; Group 2: will have the first
cord blood unit modulated with ProHema.
;
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Factorial Assignment, Masking: Open Label, Primary Purpose: Treatment
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