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Hemangioma clinical trials

View clinical trials related to Hemangioma.

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NCT ID: NCT05449106 Recruiting - Clinical trials for Brain Arteriovenous Malformations

Evaluation of Clinical Outcomes of Unruptured bAVMs Treated With Medical Management Alone Based on Multimodal CT

Start date: May 25, 2022
Phase:
Study type: Observational [Patient Registry]

The purpose of this study is to investigate the role of multimodal CT in evaluating and predicting different clinical outcomes in patients with unruptured brain arteriovenous malformations with medical management alone. This study will be undertaken in the following aspects: 1. Morphological, structural and imaging histological signal analysis based on multimodal CT to explore the relationship between imaging features and different clinical outcomes of bAVMs. 2. Hemodynamic and flow pattern analysis of local and peripheral bAVMs based on multimodal CT to explore the association between blood flow features and different clinical outcomes. 3. Based on multimodal CT and deep learning algorithms to create an automated segmentation model for bAVMs and a prediction model for distinct clinical outcomes. The obtained patient information includes: Baseline information, CT, MRI, DSA (Optional), and follow-up information. Follow-up will be undertaken at 6 months, 12 months, 24 months and 36 months after enrollment with the following primary observation. Main observation endpoints: 1. Hemorrhage events associated with bAVMs 2. New epilepsy symptoms or exacerbations 3. New neurological dysfunction(including motor dysfunction, cognitive dysfunction, etc).

NCT ID: NCT05348902 Recruiting - Clinical trials for Locked-In Syndrome;Pulmonary Arteriovenous Malformation

Locked-in Syndrome Caused by Pulmonary Arteriovenous Malformation: A Case Report

Start date: October 1, 2021
Phase:
Study type: Observational

In this case, we report a case of atresia syndrome (LIS), a serious neurological disease caused by pulmonary arteriovenous fistula (PAVM). We present a previously healthy middle-aged woman who developed atresia syndrome after severe pontine infarction due to basilar artery occlusion due to undiagnosed arteriovenous malformation. This report reviewed the medical history, post-admission examination and related literature, and concluded that PAVM should be considered as the cause of implicit stroke, especially in young patients with right-to-left shunt, and should be actively treated.

NCT ID: NCT05327309 Completed - Hemangioma Clinical Trials

Role of Propranolol as Compared to Bleomycin in Management of Hemangioma

Start date: May 8, 2015
Phase: N/A
Study type: Interventional

Infantile hemangiomas are widespread vascular tumours having incidence of 10% and most of them involute spontaneously. However, they are known to be located in proximity of vital organs and can have poor cosmetic and functional sequel if left untreated. A wide range of treatment options are available from expectant therapy to radical surgical excision. Propanolol has also been shown to be effective in treating infantile cutaneous hemangiomas. Similarly, anti-metabolite drugs as bleomycin has also shown promising results. Efficacy in terms of reduction in size of both treatments has been scarcely studied especially in Pakistan. OBJECTIVE: To assess the efficacy of oral propranolol and intraleisonal bleomycin in the treatment of infantile cutaneous hemangioma in terms of size regression

NCT ID: NCT05187923 Recruiting - Clinical trials for Infantile Hemangiomas

Computer Aided Tool for Diagnosis of Neck Masses in Children

Start date: January 1, 2021
Phase:
Study type: Observational

The aim of this study was to evaluate the diagnostic efficacy of computer aided diagnostic tool for neck masses using machine learning and deep learning techniques on clinical information and radiological images in children.

NCT ID: NCT05125471 Recruiting - Clinical trials for Arteriovenous Malformations (Extracranial)

Cobimetinib In Extracranial Arteriovenous Malformations (COBI-AVM Study)

Start date: July 26, 2022
Phase: Phase 2
Study type: Interventional

The purpose of this open-label study is to evaluate the safety and efficacy of cobimetinib in extracranial AVM.

NCT ID: NCT05106179 Enrolling by invitation - Spinal Tumor Clinical Trials

The Efficacy and Safety of Beta-blockers Drugs in Adults With Spinal Hemangioma

Start date: December 2021
Phase: Phase 4
Study type: Interventional

Spinal hemangioma is one of the most common benign vertebral tumours. Being mostly asymptomatic, it is still associated with a pain syndrome especially if encroaches into the neural canal. This study is organised to evaluate the efficacy and safety of β-blockers drugs in adults with spinal hemangioma.

NCT ID: NCT05080868 Completed - Clinical trials for Hemangioma, Capillary

Infantile Hemangioma With Minimal or Arrested Growth : Epidemiology, Clinical Characteristics and Evolution

Start date: March 23, 2021
Phase:
Study type: Observational

Infantile hemangioma (IH) is the most common vascular tumor of infancy, characterized by its clinical history. Absent at birth or present under the form of a premonitory mark, they display a rapid proliferative phase starting in the first weeks of life. Then, after a plateau phase, they slowly involute. However, a subtype of IH named "abortive", "minimal or arrested growth", "reticular" or "telangiectatic" hemangioma differs from typical IH because it doesn't have a proliferative component, or only a minimal one. This subtype of hemangioma has been recently described and data are lacking regarding its proportion among infantile hemangioma and its differences with "classic" infantile hemangioma. The aim of this study is to estimate the proportion of abortive hemangioma among infantile hemangioma. Also, the investigators aim to compare the clinical characteristics of "classic" infantile hemangiomas and abortive hemangiomas. Lastly, investigators wished to study the evolution of abortive hemangioma.

NCT ID: NCT05058482 Recruiting - Clinical trials for Intracranial Arteriovenous Malformations

Non-adhesive Liquid Embolic System in the Embolization of Cerebral Arteriovenous Malformations

Start date: December 2, 2021
Phase: N/A
Study type: Interventional

This clinical trial is to verify the safety and effectiveness of the Non-adhesive Liquid Embolic System(NALES) produced by Suzhou Hengrui Hongyuan Medical Technology Co., Ltd. in the process of clinical use to support the application of the National Medical Products Administration ( NMPA) product registration approval.

NCT ID: NCT04949815 Completed - Clinical trials for Arteriovenous Malformations

Awake Craniotomy for Arteriovenous Malformation

Start date: April 1, 2018
Phase:
Study type: Observational

The study aimed to retrospectively review cases of brain arteriovenous malformation that were surgical resected with the patient awake during the procedure.

NCT ID: NCT04836884 Completed - Clinical trials for Arteriovenous Malformations

Vascular Anomaly Pathology and Genomics Biopsy Study

Start date: April 6, 2021
Phase: N/A
Study type: Interventional

The purpose of this research is to gather information on the safety and effectiveness of core biopsy of vascular anomalies for clinical pathology and clinical genomics studies.