Clinical Trials Logo

Clinical Trial Summary

The purpose of this study is to determine the efficacy of dexamethasone for treatment of HELLP I (hemolysis, elevated liver enzymes and low platelet count) syndrome.


Clinical Trial Description

Treatment of HELLP syndrome usually is restricted to measures of support and treatment of complications. In 2005, in a subgroup analysis we showed that, among patients with HELLP 1, there were a shorter average time to platelet recovery and less duration of hospitalization in women who received dexamethasone therapy, however the importance of this finding is diminished because this was an unplanned analysis and the severity of the disease was not taken into account at randomization. ;


Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT01138839
Study type Interventional
Source Universidad del Valle, Colombia
Contact Javier Fonseca, Dr
Phone 5725583912
Email jaenfo@gmail.com
Status Recruiting
Phase Phase 3
Start date October 2009
Completion date December 2012

See also
  Status Clinical Trial Phase
Recruiting NCT03605511 - TTP and aHUS in Complicated Pregnancies
Completed NCT02911701 - Effect of Acetaminophen on Postpartum Blood Pressure Control in Preeclampsia With Severe Features Phase 4
Recruiting NCT02247297 - Pancreatic Stone Protein (PSP) in Pregnant Women
Terminated NCT04725812 - Complement Regulation to Undo Systemic Harm in Preeclampsia Phase 2
Recruiting NCT06377878 - The Preeclampsia Registry
Recruiting NCT02020174 - The Preeclampsia Registry
Recruiting NCT02920593 - A Randomized Control Trial of Vitamin D Prophylaxis in the Prevention of Hypertensive Disorders of Pregnancy Phase 4
Recruiting NCT05500989 - PlacEntal Acute Atherosis RefLecting Subclinical Atherosclerosis
Completed NCT04216706 - Early Vascular Adjustments to Prevent Preeclampsia
Recruiting NCT03834285 - Liver Disease in Pregnancy
Completed NCT00000534 - Calcium for Pre-Eclampsia Prevention (CPEP) Phase 3
Recruiting NCT02807324 - Women Specific Cardiac Recovery After Preeclampsia
Completed NCT01736826 - Free DNA and Nucleosome Concentrations in Pathological Pregnancies
Terminated NCT00711841 - Effectivity of Postpartum Dexamethasone for Women With Class I HELLP Syndrome Phase 4
Completed NCT00097110 - RCT of Antioxidant Therapy to Prevent Preeclampsia in Brazil Phase 3
Completed NCT03715647 - Correlation of Survival in Puerperae by Electrical Impedance Tomography
Completed NCT03455387 - Evaluation of the Serum Markers sFLt1 and PlGF for the Prediction of the Complications of the Placental Vascular Pathologies in the 3rd Quarter of the Pregnancy.
Completed NCT03246542 - Promising Bimarker Prediction of Outcome of HELLP Syndrome. N/A
Completed NCT03232359 - Immature Platelet Fraction as a Promising Biomarker in Prediction Outcome of HELLP Syndrome N/A
Not yet recruiting NCT06452498 - Preeclampsia Intervention Netherlands Phase 3