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HELLP Syndrome clinical trials

View clinical trials related to HELLP Syndrome.

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NCT ID: NCT02247297 Recruiting - Pregnancy Clinical Trials

Pancreatic Stone Protein (PSP) in Pregnant Women

Start date: September 2014
Phase:
Study type: Observational

This prospective, single centred cohort study evaluates the physiological course of the potentially novel biomarker PSP in pregnant women as well as its predictive role in the development of inflammatory complications during pregnancy.

NCT ID: NCT02020174 Recruiting - Preeclampsia Clinical Trials

The Preeclampsia Registry

TPR
Start date: September 1, 2013
Phase:
Study type: Observational [Patient Registry]

The purpose of The Preeclampsia Registry is to collect and store medical and other information from women who have been medically diagnosed with preeclampsia or a related hypertensive (high blood pressure) disorder of pregnancy such as eclampsia or HELLP syndrome, their family members, and women who have not had preeclampsia to serve as controls. Information from participants will be used for medical research to try to understand why preeclampsia occurs, how to predict it better, and to develop experimental clinical trials of new treatments.

NCT ID: NCT01736826 Completed - Pregnancy Clinical Trials

Free DNA and Nucleosome Concentrations in Pathological Pregnancies

Start date: June 2015
Phase:
Study type: Observational

The primary objective of this study is to demonstrate that plasma concentrations of nucleosomes and free DNA differ between three groups: 1. pregnant patients with complications typical of placental insufficiency or venous thrombosis (group P), 2. healthy women (Group T1) and 3. healthy pregnant women (Group T2).

NCT ID: NCT01138839 Recruiting - HELLP Syndrome Clinical Trials

Dexamethasone Efficacy in HELLP I Syndrome

Start date: October 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine the efficacy of dexamethasone for treatment of HELLP I (hemolysis, elevated liver enzymes and low platelet count) syndrome.

NCT ID: NCT00711841 Terminated - HELLP Syndrome Clinical Trials

Effectivity of Postpartum Dexamethasone for Women With Class I HELLP Syndrome

COHELLP
Start date: July 2011
Phase: Phase 4
Study type: Interventional

Corticotherapy accelerates maternal postpartum recovery in women with class I HELLP syndrome. The benefit of faster and better recovery would be observed in fewer complications, less utilization of blood products and shorter hospital stay.

NCT ID: NCT00097110 Completed - Pregnancy Clinical Trials

RCT of Antioxidant Therapy to Prevent Preeclampsia in Brazil

Start date: July 2003
Phase: Phase 3
Study type: Interventional

The perinatal morbidity and mortality rates for Brazil are five to ten-fold higher than those reported for upper income countries. This study tests the likelihood that the joint administration of antioxidants vitamin C (1000 mg) and vitamin E (400 IU) will reduce the incidence of preeclampsia among chronically hypertensive pregnant patients and patients with a past history of preeclampsia/eclampsia.

NCT ID: NCT00000534 Completed - Hypertension Clinical Trials

Calcium for Pre-Eclampsia Prevention (CPEP)

Start date: March 1991
Phase: Phase 3
Study type: Interventional

To evaluate the efficacy of 2 grams per day of oral calcium supplementation in reducing the combined incidence of hypertensive disorders of pregnancy: pre-eclampsia, eclampsia, and the HELLP Syndrome (hypertension, thrombocytopenia, hemolysis, and abnormal liver function). The National Institute of Child Health and Human Development (NICHD) initiated the trial in 1991, with joint funding provided by the National Heart, Lung, and Blood Institute in fiscal years 1992, 1993, and 1995.