Treating H. Pylori in Parkinson's Patients With Motor Fluctuations

Status Terminated

Clinical Trial Summary

The purpose of this study is to determine whether treatment of H. pylori (an infection of the stomach) improves treatment effectiveness in patients with Parkinson's disease and motor fluctuations.

Clinical Trial Description

Previous investigations have demonstrated that treatment of Helicobacter pylori with antibiotics leads to improved absorption and pharmacokinetics of levodopa. This may potentially benefit patients with Parkinson's disease who have motor fluctuations, specifically excessive "off" time, when their levodopa is not working to control symptoms. We seek to identify the frequency of H. pylori infection in this population using standard lab assays and determine whether eradication with standard triple therapy results in improved clinical response to medication. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00664209
Study type	Interventional
Source	University of California, Los Angeles
Contact
Status	Terminated
Phase	Phase 3
Start date	January 2008
Completion date	June 2012

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