Mbarara Acute Heart Failure Registry

Heartfailure Clinical Trial

— MAHFER  

Official title:

Mbarara Acute Heart Failure Registry: Opportunities to Improve Care of Patients Hospitalized With Acute Decompensated Heart Failure in Mbarara Regional Referral Hospital, Uganda

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02721030
• Other study ID #: 26/11-14
• Status: Completed
• Start date: March 1, 2016
• Est. completion date: March 23, 2018

Study information

• Verified date: August 2018
• Source: Mbarara University of Science and Technology
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

This is a prospective cohort to describe clinical characteristics, predictors of poor outcomes both during hospitalization and at home, functional status, and quality of life among patients aged 13 years or more, consecutively admitted with acute decompensated heart failure at Mbarara Regional Referral Hospital.

Description:

This is a prospective observational cohort study to collect comprehensive data of heartfailure patients during and after hospitalization for acute heart failure at Mbarara Regional Referral Hospital (MRRH), Uganda. The investigators will collect sociodemographic, clinical, quality of life, functional status, and clinical cardiovascular disease measures during hospitalization and follow up for up to 1 year from the date of enrollment.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 217
• Est. completion date: March 23, 2018
• Est. primary completion date: March 1, 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: 13 Years and older

Eligibility

Inclusion Criteria:

• Patients admitted with a confirmed clinical diagnosis of acute heartfailure aged 13 years or above at Mbarara Regional Referral Hospital, Uganda

Exclusion Criteria:

• Body swelling from kidney disease, liver disease or malnutrition.

• Acute kidney disease with no previous history/documentation of heart disease.

• History suggestive of chronic kidney disease with no previous history/documentation of heart disease.

• History suggestive of chronic liver disease with no previous history/documentation of heart disease.

Related Conditions & MeSH terms

• Heart Failure
• Heartfailure

Locations

Country	Name	City	State
Uganda	Mbarara Regional Referral Hospital	Mbarara	N/A = Not Applicable

Sponsors (3)

Lead Sponsor	Collaborator
Mbarara University of Science and Technology	Abbott Point of Care, University of Virginia

Country where clinical trial is conducted

Uganda, 

References & Publications (1)

Abeya FC, Lumori BAE, Akello SJ, Annex BH, Buda AJ, Okello S. Incidence and predictors of 6 months mortality after an acute heart failure event in rural Uganda: The Mbarara Heart Failure Registry (MAHFER). Int J Cardiol. 2018 Aug 1;264:113-117. doi: 10.10 — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	All-cause mortality		1 year
Secondary	Length of hospitalization	Length of hospital stay	1 year
Secondary	Quality of life using the SF-36 questionnaire	Quality of life will be measured using SF-36 questionnaire.	1 year
Secondary	Functional status using the Kansas city cardiomyopathy questionnaire	Kansas city cardiomyopathy questionnaire will be used to measure functional status during hospitalization and quarterly after hospitalization with acute heartfailure.	1 year