Mid-Q Response Study

Status Completed

Clinical Trial Summary

The Mid-Q Response study is a prospective, multi-center, randomized controlled, interventional, single-blinded, post-market study. The purpose of the Mid-Q Response study is to test the hypothesis that the AdaptivCRT (aCRT) algorithm is superior to standard CRT therapy regarding patient outcomes in CRT indicated patients with moderate QRS duration, preserved atrioventricular (AV) conduction and left bundle branch block (LBBB). The study will be executed at approximately 60 centers in Asia. The subjects will be randomly assigned in a 1:1 ratio to the aCRT ON (Adaptive Bi-V and LV) group or the aCRT OFF (Nonadaptive CRT) group. The primary objective is to test the hypothesis that aCRT ON increases the proportion of patients that improve on the Clinical Composite Score (CCS) compared to aCRT OFF at 6 months of follow-up.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Bundle-Branch Block
Heart Failure
Heart Failure NYHA Class II
Heart Failure NYHA Class III
Heart Failure NYHA Class IV
Heart Failure With Reduced Ejection Fraction (HFrEF)
Left Bundle-Branch Block

Clinical Trial Details

NCT number	NCT04180696
Study type	Interventional
Source	Medtronic Bakken Research Center
Contact
Status	Completed
Phase	N/A
Start date	January 23, 2020
Completion date	March 28, 2024

View Details

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