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A Pilot Study of Recombinant Human Relaxin (rhRlx) in Compensated Congestive Heart Failure

Heart Failure, Congestive Clinical Trial

Official title:
A Pilot Safety and Dose-Finding Trial of Intravenous Recombinant Human Relaxin (rhRlx) in Compensated Congestive Heart Failure

Clinical Trial Summary

This trial is a single center, open-label, dose-finding study of recombinant human relaxin (rhRlx) given intravenously (IV) to patients with stable, compensated CHF.

Clinical Trial Description

Serial cohorts of patients with stable CHF will be enrolled upon meeting eligibility criteria. Dose escalation will be guided by hemodynamic response, safety and tolerability. The effects of rhRlx on hemodynamics will be assessed. ;

Study Design

Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00259116
Study type Interventional
Source Corthera, Inc.(formerly BAS Medical, Inc.), a member of the Novartis group of companies
Contact
Status Completed
Phase Phase 2
Start date November 2005
View Details
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