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Growth Hormone and Heart Failure

Heart Failure, Congestive Clinical Trial

Official title:
Modifications of the Growth Hormone/IGF1 Axis in Heart Failure Patients

Clinical Trial Summary

Heart failure induces modification in several neurohormonal systems. The aim of this study is to determine if the growth hormone/IGF1 axis is modified in heart failure patients compared to healthy volunteers.

Clinical Trial Description

One hundred and sixty three heart failure patients were evaluated by clinical examination, echocardiography, exercise test and measurement of blood BNP. Growth hormone and IGF-1 plasma levels were determined in each patient. The same biological measurements were performed in a group of 148 healthy controls. Comparisons were performed between groups for Growth hormone plasma level, IGF-1 plasma level and Growth hormone/IGF-1 index. A correlation between the severity of heart failure and the different biological parameters was searched. ;

Study Design

Observational Model: Case Control, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00190359
Study type Observational
Source Assistance Publique - Hôpitaux de Paris
Contact
Status Terminated
Phase N/A
Start date September 2000
Completion date February 2003
View Details
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