Heart Decompensation Clinical Trial
Official title:
LDL Apheresis for the Treatment of Congestive Heart Failure
A pilot study to examine the effects of LDL-Apheresis on patients with Stage III Congestive
Heart Failure.
Study hypothesis: Decreased blood viscosity from receiving LDL-apheresis will decrease
workload on the heart and improve symptoms associated with the progression of Congestive
Heart Failure
Patients who qualify for the study will receive 7 bi-weekly LDL-Apheresis treatments with the Kaneka Liposorber device. Patients will assess their CHF symptoms using the KC Cardiomyopathy questionnaire prior to each treatment. Blood levels of certain indices related to CHF and safety profile labs will be drawn before and after the first and last treatment. ;
Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT05747820 -
Multiparametric Assessment of Cardiac Congestion in Outpatient Worsening Heart Failure
|
||
Recruiting |
NCT02051985 -
Early-start Exercise Training in Subacute Heart Failure
|
N/A | |
Terminated |
NCT02859636 -
Pronostic Value of Endothelial Dysfunction in Heart Failure
|
N/A | |
Completed |
NCT00813202 -
An Open-label, One-arm, Study to Evaluate the Hemodynamic Changes and Safety of Nesiritide for Acute Decompensated Heart Failure
|
Phase 3 | |
Withdrawn |
NCT00166010 -
Effects of Nesiritide in Pediatric Patients With Heart Failure
|
N/A | |
Completed |
NCT00364416 -
Longitudinal Registry for Advanced Heart Failure Patients
|
N/A | |
Completed |
NCT00366639 -
Registry for Acute Decompensated Heart Failure Patients
|
N/A | |
Completed |
NCT00288730 -
A Study of Two Doses of Intravenous NATRECOR hBNP (Nesiritide) in Patients With Worsening Congestive Heart Failure Who Have Difficulty Breathing at Rest
|
Phase 3 | |
Completed |
NCT03515980 -
An Investigational Study of Experimental Medication BMS-986231 Given in Participants With Different Levels of Liver Function
|
Phase 1 | |
Completed |
NCT00475852 -
A Study Testing the Effectiveness of Nesiritide in Patients With Acute Decompensated Heart Failure
|
Phase 3 | |
Completed |
NCT00364325 -
Registry for Acute Decompensated Heart Failure Patients Admitted to the ER
|
N/A | |
Recruiting |
NCT04703504 -
RAndomized Controlled Trial of a Multiple INtervention proGram to Decrease Heart Failure Rehospitalization
|
N/A | |
Withdrawn |
NCT02649998 -
Short-term Efficacy of Furosemide, Isosorbide Dinitrate and Their Combination in ADHF
|
N/A | |
Not yet recruiting |
NCT02324400 -
Pilot Study for the Evaluation of the Safety and Performance of the RenaSense System in Hospitalized Acute Decompensated Heart Failure Patients
|
Phase 1/Phase 2 | |
Completed |
NCT00259038 -
Evaluation of the Effects of Carperitide in Patients With Congestive Heart Failure
|
Phase 2 | |
Completed |
NCT00271557 -
A Study to Develop Additional Safety and Clinical Experience With NATRECOR hBNP (Nesiritide) in the Treatment of Patients With Worsening Congestive Heart Failure Who Require Inpatient Intravenous Therapy With Medications That Influence the Tone and Caliber of Blood Vessels
|
Phase 3 | |
Completed |
NCT03730961 -
An Investigational Study of Continuous 8-Hour Intravenous Administrations of BMS-986231 in Participants With Heart Failure and Reduced Heart Function Given a Standard Dose of Loop Diuretic
|
Phase 2 | |
Completed |
NCT06255418 -
Big Data to Assess the Healthcare and Health Outcomes Burden of Acute Coronary Syndromes Complicated With Heart Failure
|
||
Terminated |
NCT04198779 -
Interest of the Smartphone Application "MonCÅ“ur" in the Follow-up of Patients With Heart Failure
|
N/A | |
Completed |
NCT04698954 -
Evaluating the Adherence Improving Self-Management Strategy Intervention in Chronic Heart Failure Patients
|
N/A |