Clinical Trials Logo

Heart Arrest clinical trials

View clinical trials related to Heart Arrest.

Filter by:

NCT ID: NCT00880087 Completed - Cardiac Arrest Clinical Trials

Therapeutic Hypothermia to Improve Survival After Cardiac Arrest in Pediatric Patients-THAPCA-IH [In Hospital] Trial

THAPCA-IH
Start date: September 2009
Phase: N/A
Study type: Interventional

Cardiac arrest is a sudden, unexpected loss of heart function. Therapeutic hypothermia, in which the body's temperature is lowered and maintained several degrees below normal for a period of time, has been used to successfully treat adults who have experienced cardiac arrest. This study will evaluate the efficacy of therapeutic hypothermia at increasing survival rates and reducing the risk of brain injury in infants and children who experience a cardiac arrest while in the hospital.

NCT ID: NCT00879892 Completed - Clinical trials for Ischemic Brain Injury

Effect of Xenon and Therapeutic Hypothermia, on the Brain and on Neurological Outcome Following Brain Ischemia in Cardiac Arrest Patients

Xe-hypotheca
Start date: May 2009
Phase: Phase 2
Study type: Interventional

The main purpose of this study is to explore whether xenon is neuroprotective in humans. In addition, the purpose is to explore the underlying mechanisms for the possible synergistic neuroprotective interaction of xenon and hypothermia in patients suffering cerebral ischemia post cardiac arrest, by undertaking brain imaging to evaluate their effects on cerebral hypoxia, neuronal loss and mitochondrial dysfunction. In addition, the investigators aim to correlate these findings with neurological outcome to determine surrogate markers of favourable clinical outcome at six months.

NCT ID: NCT00878644 Completed - Cardiac Arrest Clinical Trials

Therapeutic Hypothermia to Improve Survival After Cardiac Arrest in Pediatric Patients-THAPCA-OH [Out of Hospital] Trial

THAPCA-OH
Start date: September 2009
Phase: Phase 3
Study type: Interventional

Cardiac arrest is a sudden, unexpected loss of heart function. Therapeutic hypothermia, in which the body's temperature is lowered and maintained several degrees below normal for a period of time, has been used to successfully treat adults who have experienced cardiac arrest. This study will evaluate the efficacy of therapeutic hypothermia at increasing survival rates and reducing the risk of brain injury in infants and children who experience a cardiac arrest while out of the hospital.

NCT ID: NCT00870610 Completed - Hypothermia Clinical Trials

Jugular Venous Oxygen Saturation During Therapeutic Hypothermia After Cardiac Arrest

SjO2
Start date: November 2011
Phase: N/A
Study type: Observational

The purpose of this study is to understand what happens to cerebral metabolism during therapeutic hypothermia for hypoxic brain injury following cardiac arrest.

NCT ID: NCT00848588 Completed - Cardiac Arrest Clinical Trials

A Survey of Factors Associated With the Successful Recognition of Agonal Breathing and Cardiac Arrest.

Start date: June 2009
Phase:
Study type: Observational

The overall goal of this pilot study is to design and conduct a survey of 9-1-1 call takers in the province of Ontario, Canada to better understand the factors associated with the successful identification of cardiac arrest (including victims with agonal breathing) over the phone. Specific objectives are: 1. To conduct iterative semi-structured interviews to identify behavioural factors influencing identification of cardiac arrest by 9-1-1 call takers; 2. To develop a survey instrument about behavioural factors influencing the ability of 9-1-1 call takers to identify cardiac arrest based on a systematic review of the literature, the results of the semi-structured interviews, and theoretical constructs from the Theory of Planned Behaviour; and 3. To conduct a survey among Ontario 9-1-1 call takers using the survey instrument, and to identify factors and strategies that might be targeted by Knowledge Translation interventions.

NCT ID: NCT00843297 Completed - Cardiac Arrest Clinical Trials

COOL-Trial: Outcome With Invasive and Non-invasive Cooling After Cardiac Arrest

COOL
Start date: April 2008
Phase: Phase 4
Study type: Interventional

Sudden cardiac arrest (SCA) remains one of the major leading causes of death. Cognitive deficits are common in survivors of SCA. Postresuscitative mild induced hypothermia (MIH) lowers mortality and reduces neurologic damage after cardiac arrest. The investigators evaluated the efficacy and side effects of therapeutic hypothermia in an unselected group of patients after SCA.

NCT ID: NCT00827957 Completed - Cardiac Arrest Clinical Trials

Comparing Therapeutic Hypothermia Using External and Internal Cooling for Post-Cardiac Arrest Patients

Hypothermia
Start date: October 2008
Phase: Phase 4
Study type: Interventional

Controlled therapeutic hypothermia is a method of preserving neurological function post-resuscitation.It has been associated with improved functional recovery and reduced histological deficits in animal models of cardiac arrest.

NCT ID: NCT00808236 Completed - Cardiac Arrest Clinical Trials

Pre-ROSC Intra-Nasal Cooling Effectiveness

PRINCE
Start date: November 2008
Phase: N/A
Study type: Interventional

The purpose of the study was to demonstrate the safety and feasibility of early intranasal cooling prior to return of spontaneous circulation (ROSC) in the emergency medical services (EMS) environment. It was hypothesized that cooling during the resuscitation attempt would increase ROSC and subsequent survival. The study was not powered to demonstrate statistically-significant differences in any outcome parameter, but was intended as an exploratory study only.

NCT ID: NCT00797680 Completed - Cardiac Arrest Clinical Trials

Duration of Hypothermia for Neuroprotection After Pediatric Cardiac Arrest

Start date: October 2008
Phase: Phase 2
Study type: Interventional

In this study, children who survive cardiac arrest will be evaluated whether 24 or 72 hours of whole body hypothermia (cooling) during recovery is better to help prevent brain injury and improve outcome. The investigators will also test the safety of cooling patients for 24 and 72 hours. The investigators hypothesize that 72 hours of cooling will be more beneficial than 24 hours without compromising safety.

NCT ID: NCT00780299 Completed - Cardiac Arrest Clinical Trials

Hemodynamic Efficiency of an Hemodialysis Treatment With High Permeability in Post-resuscitation Shock

Hyperdia
Start date: November 2, 2008
Phase: Phase 3
Study type: Interventional

Rationale: Despite spontaneous cardiac activity recovery, a shock occurs in more than half of patients after resuscitation for cardiac arrest. This acute circulatory insufficiency presents similar characteristics with septic shock and is responsible of most early deaths. Most frequently, usual treatments are unable to control this shock and to avoid the appearance of multiple organ failure. Aim of the study: In addition to conventional therapeutics, an early plasma epuration of inflammatory mediators (HDHP) could be able to improve hemodynamic parameters and to reduce the shock duration. This improvement could have an impact on multiple organ dysfunctions and also on early mortality.