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Heart Arrest clinical trials

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NCT ID: NCT02356029 Completed - Clinical trials for Cardiopulmonary Arrest

Perception of Inappropriate CPR: a Multicenter International Cross-sectional Survey

REAppropriate
Start date: March 2015
Phase:
Study type: Observational

The primary objective of this study is to determine how often cardiopulmonary resuscitation (CPR) is perceived as inappropriate by Healthcare Providers (HCPs) working in prehospital Ambulance Services and Emergency Departments. Perception of inappropriate CPR is defined as resuscitation efforts perceived by HCPs as disproportionate to the expected prognosis of the patient in terms of survival or quality of life. When a HCP perceives CPR as inappropriate, this may cause moral and emotional distress. This perception may be modulated by the personal background and professional role of the HCP, but also by his/her working conditions. Apart from the workload, the resulting distress can be influenced by the way non-technical skills are developed within the team and the ethical environment in which the HCP functions. Frequent exposure to similar patient care situations and/or a professional environment not acknowledging the distress may lead to deficient coping mechanisms and accumulation of moral distress. This may be associated with job leave, burnout and a decreased quality of patient care. Acute distress may also influence the quality of care provided to actual and future patients. Secondary objectives of the study are to evaluate whether perceived inappropriateness of CPR is not only associated with patient related factors but also with personal characteristics and work related factors. Potential consequences for HCP's like moral distress and intentional job leave will be assessed.

NCT ID: NCT02349074 Completed - Clinical trials for Out-of-hospital Cardiac Arrest

Digestive ENdoscopy afTeR Out-of-hospitAl Cardiac arresT

ENTRACT
Start date: November 12, 2014
Phase: N/A
Study type: Interventional

Post-cardiac arrest ischemia/reperfusion phenomenon led to organs injury and failure. Among the different organs, gastro-intestinal tract injury could contribute to post-cardiac arrest shock. The ischemic injury of the gastro-intestinal (GI) tractus is suggested by abnormalities in digestive biomarkers and by the frequent endotoxemia after CA. However, direct mucosal damage has not been clearly demonstrated after OHCA. The real incidence of ischemic lesions of GI tract and their potential involvement in the post-CA shock is therefore unknown. We propose an original clinical research program aimed at rigorously determining the incidence of upper GI lesions after OHCA and analyzing their contribution to the severity of post-CA shock through a prospective, interventional, multicentric study

NCT ID: NCT02327871 Completed - Cardiac Arrest Clinical Trials

Esophageal Temperature Management After Cardiac Arrest

THE-COOL
Start date: December 2014
Phase: N/A
Study type: Interventional

To control patient's body temperature remains of major importance especially after cardiac arrest (CA). Therapeutic hypothermia (TH) targeted to 32-34°C is now recommended for most unconscious CA patients. However, available modalities for inducing TH have a number of technical (side effects), logistical (difficulties of placement), and financial (cost) barriers. The Esophageal Cooling Device (ECD) is a multi-chambered silicone heat exchanger placed in the esophagus providing highly efficient heat transfer to a patient. The ECD is a device that potentially improves the effectiveness of TH in minimizing the risks of existing methods (such as invasive cooling). Initial mathematical and animal studies have shown strong support for the efficacy and safety of the ECD. Placement of a naso-gastric probe is a systematic standard of care for all unconscious patients suffering from CA. The present study will replace the usual naso-gastric probe by the ECD that can be used for gastric suctioning as usually done in such patients. The aim of this prospective, interventional study is to assess the feasibility and safety of the ECD in resuscitated CA-patients and treated with 32-34°C targeted TH. The primary outcome is the feasibility of inducing, maintaining, and rewarming patients from TH using the ECD (cooling rate, rewarming rate, and the percent of time within goal temperature during the goal-temperature maintenance period). Evaluation of adverse events (including cardiac arrhythmias, severe bradycardia, myocardial infarction/re-infarction, dysphagia, odynophagia, aspiration pneumonia, non-aspiration pneumonia, esophageal reflux and injury, and esophagitis) will be closely monitored during the whole period of the targeted temperature management (secondary endpoint).

NCT ID: NCT02327026 Completed - Clinical trials for Out-of-hospital Cardiac Arrest

Tracheal Intubation vs. Bag-valve-mask Ventilation in Patients With Out-of-Hospital Cardiac Arrest _ CAAM STUDY

CAAM
Start date: March 9, 2015
Phase: N/A
Study type: Interventional

The aim of this study is to improve the management of patients in cardiac arrest, and this by comparing two initial airway management methods: Tracheal intubation and bag-valve-mask ventilation. The survival rate at 28-day with favorable neurological function will be compared in the tracheal intubation group versus the bag-valve-mask group

NCT ID: NCT02322359 Completed - Cardiac Arrest Clinical Trials

Compression Is Life In Cardiac Arrest - Fatigue Study

CILICA-FS
Start date: August 2014
Phase: N/A
Study type: Observational

Context: Chest compressions represent an important physical effort leading to fatigue and cardiopulmonary resuscitation quality degradation. Despite a known harmful effect of chest compressions interruptions, current guidelines still recommend provider switch every 2 minutes. Feedback impact on chest compressions quality during an extended cardiopulmonary resuscitation remains to be assessed. Study design: simulated prospective monocentric randomized crossover trial. Participants and methods: Sixty professionals rescuers of the pre-hospital care unit of University Hospital of Caen (doctors, nurses and ambulance drivers) are enrolled to performed 10 minutes of continuous chest compression on manikin (ResusciAnne®, Laerdal), twice, with and without a feedback device (CPRmeter®). Correct compression score (the main criterion) is defined by reached target of rate, depth and leaning at the same time (recorded continuously). Hypothesis: Feedback device delay fatigue effect arises during cardiopulmonary resuscitation.

NCT ID: NCT02303548 Completed - Cardiac Arrest Clinical Trials

Bicarbonate in Patients With Out-of-hospital Cardiac Arrest

Start date: October 2014
Phase: Phase 2
Study type: Interventional

A pilot study to evaluate the effect of sodium bicarbonate administration on cardiopulmonary resuscitation results and outcomes in cardiac arrest patient with severe metabolic acidosis.

NCT ID: NCT02295618 Completed - Cardiac Arrest Clinical Trials

ETI During Intubation

SL
Start date: November 2014
Phase: N/A
Study type: Interventional

The objective of this study is to compared effectiveness of intubation using ETView VivaSight SL and standard tracheal tube during resuscitation performed by a novice-physicians.

NCT ID: NCT02292147 Completed - Clinical trials for Out of Hospital Cardiac Arrest

Functional Outcome After Cardiac Arrest

HANOX
Start date: March 13, 2013
Phase:
Study type: Observational

Descriptive and prognosis study of the functional outcome after cardiac arrest for the patients awake within the first 15 days.

NCT ID: NCT02291653 Completed - Cardiac Arrest Clinical Trials

Pediatric Endotracheal Intubation

EMS
Start date: November 2014
Phase: N/A
Study type: Interventional

We hypothesized that the McGrath MAC EMS is beneficial for intubation of pediatric manikins while performing CPR. In the current study, we compared effectiveness of the McGrath MAC EMS and MIL laryngoscopes in child resuscitation with and without CC.

NCT ID: NCT02289872 Completed - Cardiac Arrest Clinical Trials

Pediatric Intubation

ETICPR
Start date: November 2014
Phase: N/A
Study type: Interventional

The aim of the study was to compare time and success rates of TruView PCD video laryngoscope and Macintosh laryngoscope for the pediatric emergency intubation with three airway scenarios in a standardized manikin model.