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Heart Arrest clinical trials

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NCT ID: NCT02494089 Completed - Heart Arrest Clinical Trials

Analysis of the Stress Induced by in Situ Simulation

SIMSTRESS
Start date: June 2015
Phase: N/A
Study type: Observational

Vulnerability to psychologic distress induced by in situ simulation. Objectives: Psychological evaluation at short and long term on working satisfaction, mental health, and acute stress after in situ simulation. Analysis of the stress vulnerability induced by simulation. Design: non interventional study. Primary outcome: Psychologic distress analysis with validated psychologic distress inventory (Job Satisfaction Survey (JSS), General Health Quality (GHQ), Impact of Event Scale Revisited (IESR), State-Trait Anxiety Inventory-A (STAI-A), State-Trait Anxiety Inventory -B (STAI-B)).

NCT ID: NCT02486211 Completed - Heart Arrest Clinical Trials

Amantadine to Speed Awakening After Cardiac Arrest

AWAKE
Start date: September 2015
Phase: Phase 2
Study type: Interventional

This study evaluates if amantadine will increase the rate of awakening in patients resuscitated from cardiac arrest but comatose (not following commands) after their resuscitation. Half of the participants will receive amantadine and the other will receive placebo.

NCT ID: NCT02483546 Completed - Cardiac Arrest Clinical Trials

High Fidelity Simulation vs Standard Teaching Training of Cardiac Resuscitation

SIMCARE
Start date: January 2014
Phase: N/A
Study type: Interventional

High fidelity Simulation has spread from anesthesiology to other disciplines such as internal medicine, pediatrics, and emergency medicine . Over the past decade, the use of simulation in medical education has increased exponentially. The term ''simulation'' spans a wide variety of formats, from the low-tech actor portraying a standardized patient to high-fidelity mannequin-based human patient simulation (HPS). HPS is able of both simulating realistic patient encounters and giving real-time, physiologically accurate feedback. Studies thus far show that use of simulation in training medical students and residents is helpful in strengthening students' knowledge and in evaluating their performance. Students appreciate simulation-based education as ''an opportunity to learn new skills in a safe environment .

NCT ID: NCT02479152 Completed - Cardiac Arrest Clinical Trials

The Haemodynamic Effects of Mechanical Standard and Active Chest Compression-decompression During Out-of-hospital CPR

Start date: April 2015
Phase: N/A
Study type: Interventional

The aim of this randomized out-of-hospital cardiopulmonary resuscitation study is to investigate haemodynamics generated by the standard mechanical external chest compression device (LUCAS™ 2) compared to a new version generating chest compressions and active decompression above the initial starting position of the suction cup (LUCAS™ 2AD).

NCT ID: NCT02473679 Completed - Heart Arrest Clinical Trials

Influence of the Education in Layperson in Out of Hospital Resuscitation

Start date: January 2003
Phase: N/A
Study type: Observational

Cardiac arrest occurs frequently and the outcome after out-of-hospital resuscitation is often fatal. Disturbing is that more than half of the surviving patients suffer from permanent impairment of cognitive functions, such attention, memory and executive functioning. With all the efforts to achieve a high quality initial resuscitation management the time delay between cardiac arrest and the beginning the initial resuscitation maneuver is the main reason for the still poor outcome. To shorten this fatal time delay, current efforts of national and supranational health authorities aime at the non-medically trained lay person, who should carry out basic life support directly on the scene supported by the use of public available semi-automatic defibrillators (AED).

NCT ID: NCT02458820 Completed - Seizures Clinical Trials

Prompt Diagnosis and Treatment of Subclinical Seizures After Cardiac Arrest

Start date: June 2015
Phase: N/A
Study type: Interventional

Non-convulsive seizures (NCS) following cardiac arrest are common and are associated with worse neurologic outcomes and increased mortality. More prolonged seizures (status epilepticus) are associated with worse outcomes. Earlier diagnosis and treatment of seizures may lead to earlier termination of seizures and decreased seizure burden. This study will evaluate whether bedside intensive care unit (ICU) provider interpretation of a type of EEG called DSA EEG can be used by non-neurologists to diagnosis seizures more rapidly than continuous EEG's routinely read by neurologists.

NCT ID: NCT02454257 Completed - Critical Illness Clinical Trials

Risk Modelling for Quality Improvement in the Critically Ill: Making Best Use of Routinely Available Data

Start date: August 1, 2015
Phase:
Study type: Observational

The aim of the proposed study is to better understand the epidemiology of, risk factors for and consequences of critical illness leading to improvements in the risk models used to underpin national clinical audits for adult general critical care, cardiothoracic critical care and in-hospital cardiac arrest using data linkage with other routinely collected data sources.

NCT ID: NCT02450071 Completed - Clinical trials for Traumatic Brain Injury

Pre-Hospital Advanced Airway Management in the Nordic Countries

PHAST
Start date: May 1, 2015
Phase: N/A
Study type: Observational

Pre-Hospital Advanced Airway Management (PHAAM) is a potentially lifesaving intervention. A recent Danish multicentre single country study demonstrated a 99,7% incidence of successful anaesthesiologist pre-hospital endotracheal intubation, with a PHAAM-related complication rate of 7.9%. A London study revealed a significantly higher intubation failure rate among non-anaesthesiologist physicians. In Scandinavia different types of emergency medical services (EMS) and professions provide PHAAM. The success rate of prehospital endotracheal intubation (PHETI), incidence of difficult intubation and complications in the Nordic countries is not known. The aim of this study is to define PHAAM success rate and complications in different types of Nordic EMS organisations and physician critical care teams. The study is a prospective observational study with collection of PHAAM data according to the template by Sollid et al. in the 12 participating Nordic Countries EMS/HEMS centres and physician critical care teams. The primary endpoint is PHETI success on ≤2 attempts and no complications.

NCT ID: NCT02442791 Completed - Cardiac Arrest Clinical Trials

GLP-1 Analogs for Neuroprotection After Cardiac Arrest

GLIP1
Start date: June 2014
Phase: N/A
Study type: Interventional

Experimental studies and previous clinical trials suggest neuroprotective effects of GLP-1 analogs in various degenerative neurological diseases, and in hypoxic brain injuries in experimental designs. This study is designed as a safety and feasibility study with patients randomized 1:1 to receive GLP-1 analogs immediately after hospital admission after out of hospital cardiac arrest.

NCT ID: NCT02419573 Completed - Cardiac Arrest Clinical Trials

Pragmatic Airway Resuscitation Trial

PART
Start date: December 1, 2015
Phase: N/A
Study type: Interventional

The primary objective of the trial is to determine if 72-hour survival after out-of-hospital cardiac arrest (OHCA) is improved with initial endotracheal intubation (ETI) over initial laryngeal tube (LT) airway management strategies.