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Heart Arrest clinical trials

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NCT ID: NCT05264246 Recruiting - Cardiac Arrest Clinical Trials

Evaluation of an Anti-Shivering Protocol Cardiac Arrest

Start date: September 15, 2021
Phase:
Study type: Observational

This will be a single center, retrospective, before-and-after, chart review of all patients undergoing TTM between June 1, 2017 and May 31, 2021 at MDMC. Initiation of the new TTM protocol occurred on April 22, 2019.

NCT ID: NCT05253937 Completed - Clinical trials for Cardiopulmonary Arrest

Impact of Intracoronary Versus Intravenous Epinephrine Administration During Cardiac Arrest .

(iCPR)
Start date: April 1, 2018
Phase:
Study type: Observational

In hospital cardiac arrest (IHCA) is a major challenge imposed on almost all health care systems worldwide. Despite significant progress in cardiopulmonary resuscitation in the past few years, outcomes remain relatively poor with an approximate 49 % survival rate. Epinephrine administration remains a cornerstone in the treatment of cardiac arrest. However, the preferred route of administration remains a matter of debate within the medical community . Various routes of administration, including intravenous, intramuscular, intraosseous and endotracheal routes have been studied. Initially, American guidelines for the treatment of cardiac arrest recommended injection of 0.5 mg of epinephrine directly into the right ventricle through the parasternal approach, aiming to achieve higher peak intracardiac concentrations and a more central effect, however the intravenous route remained preferable due to its feasibility and safety . To our knowledge, intra-coronary epinephrine administration for intraprocedural cardiac arrest has not been evaluated or compared with other routes of administration.

NCT ID: NCT05236920 Withdrawn - Clinical trials for Ventricular Tachycardia

Utility and Procedural Feasibility of REBOA Operationalized for Non-Trauma Application (UP-FRONT)

UP-FRONT
Start date: October 1, 2022
Phase: N/A
Study type: Interventional

Single center randomized-controlled trial in out-of-hospital cardiac arrest (OHCA) patients. This study will investigate the feasibility and utility of the Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) procedure using a REBOA catheter device in patients who have experienced an OHCA and have not regained return of spontaneous circulation (ROSC).

NCT ID: NCT05218278 Recruiting - Clinical trials for Out-Of-Hospital Cardiac Arrest

NFL Dynamics as a Predictor Factor in Patients With Out of Hospital Cardiac Arrest

Start date: January 1, 2022
Phase:
Study type: Observational

To investigate the pharmacodynamics of light chain of NFL in patients with out-of hospital cardiac arrest after successful resuscitation and determine the difference in the serum levels of NFL in patients with favorable neurological outcome compared to those with non-favorable neurological outcome.

NCT ID: NCT05208645 Not yet recruiting - Clinical trials for Arrested Pregnancies

The Place of Men in Arrested Pregnancies

PHGA
Start date: January 31, 2022
Phase:
Study type: Observational

An terminated pregnancy is defined as the cessation of cardiac activity before 14 weeks of amenorrhea. This early interruption of gestation can be induced by pathological, traumatic or idiopathic causes. In any case, it remains a physically and psychologically trying event for the woman, the couple as well as for the man. Indeed, the loss of this embryo, which measures only a few millimeters, corresponds to the loss of a child for the triad: woman, man, couple. The termination of this pregnancy is experienced as a bereavement for the future parents. The stopped pregnancy has always been a taboo in the society. The proof being that it was not until the 1980s that this was considered mourning and its psychological consequences were studied. Following these studies, psychological follow-ups are democratized and are thus offered to women. However, when is it men? The investigators have always put the woman at the center of the care process. Which is legitimate. However, the man is often seen as "the person who influences the woman". This default categorization marginalizes the man who would like to be an actor in the care of his partner. In fact, men are increasingly asking to support women in their gynecological care procedures. Unfortunately, for lack of measures put in place. The men are more than abandoned.

NCT ID: NCT05205031 Active, not recruiting - Cardiac Arrest Clinical Trials

Intravenous vs. Intraosseous Vascular Access During Out-of-Hospital

IVIO
Start date: March 1, 2022
Phase: Phase 4
Study type: Interventional

The "Intravenous vs. Intraosseous Vascular Access During Out-of-Hospital Cardiac Arrest (IVIO)"-trial is an investigator-initiated, randomized, parallel group, patient and outcome assessor-blinded, superiority trial of intravenous vs. intraosseous vascular access during adult out-of-hospital cardiac arrest. The intraosseous group will be further randomized to humeral vs. tibial access. The trial will be conducted in the Central Denmark Region. The primary outcome will be sustained return of spontaneous circulation, and 762 patients will be included. Key secondary outcomes include survival at 30 days and survival at 30 days with a favorable neurological outcome.

NCT ID: NCT05201495 Completed - Clinical trials for Sudden Cardiac Arrest

The Jewel IDE Study

Start date: January 12, 2022
Phase: N/A
Study type: Interventional

The Jewel IDE Study: A Clinical Evaluation of the Jewel P-WCD in Subjects at High Risk for Sudden Cardiac Arrest. ("JEWEL")

NCT ID: NCT05192772 Recruiting - Cardiac Arrest Clinical Trials

Early Neurological Assessment With Pupillometry in Cardiac Arrest During Resuscitation

EASY-CARE
Start date: December 1, 2022
Phase:
Study type: Observational

Easy Care study wants to demonstrate a correlation between intra-CPR infrared quantitative pupillometry and return of spontaneous circulation (ROSC). Neurological pupil index (NPi) will be used alone and in association with end-tidal CO2.

NCT ID: NCT05191992 Completed - Clinical trials for Cardiopulmonary Arrest With Successful Resuscitation

Basic Life Support (BLS) Training by Homemade Manikin

Start date: June 1, 2021
Phase: N/A
Study type: Interventional

The experimentally planned research was carried out between the dates of 01.06.2021-10.11.2021 with the students of ……………. Faculty of Health Sciences, Department of Nursing. The students, whose informed consent form was obtained beforehand, were provided to fill in the Participant Diagnosis Form and the Basic Life Support Information Evaluation Form questioning their demographic characteristics before the education. Afterward, with the e-learning method (Perculus 3 Virtual Classroom), the students have given Basic Life Support training in accordance with the AHA 2020 guidelines through a Powerpoint presentation. After the training, the information evaluation form was filled in again by the students in an electronic environment. Afterward, the students were shown how to make a Basic Life Support manikin with a pillow and plastic pet bottle, and the CPR performance was explained with the manikin. The students who made the performance in the home environment made a video recording and uploaded the videos they took to the system within 1 day. Two researchers who are experts in their fields made the video evaluations according to the basic life support performance evaluation form. Later, in the online debriefing session, the pros and cons of the training were discussed with the students, and after 1 month, knowledge and skills were evaluated again and the level of permanence on the subject was measured.

NCT ID: NCT05187299 Not yet recruiting - Education Clinical Trials

Use of an Observer Tool to Improve Learning Outcomes for Cardiac Arrest Management

Start date: January 10, 2022
Phase: N/A
Study type: Interventional

Only approximately 10.4% of patients with out-of-hospital cardiac arrest (OHCA) survive their initial hospitalization. The very early management of cardiac arrest is indeed considered an extremely important criterion to improve patients' outcome. Despite recent advances and improved results, outcomes remain poor, especially because bystanders are not well trained to manage such a crisis situation. According to the International Liaison Committee on Resuscitation, teaching and learning the knowledge, skills and attitudes of resuscitation with the ultimate aim of improving patient survival after cardiac arrest is thus an essential goal. Teaching and learning strategies are numerous and have been well described and reviewed recently. Considering initial training methods already requires attention as study results often fail to show complete and effective learning after the initial training. Educational efficiency may be improved by several means (for example use of digital media) but it is now clear that more effective training strategies, i.e. those focusing on the cognitive process which leads to inclusion in memory), are needed. One recently introduced strategy, mainly in the field of simulation, is the use of observer tools. It has been shown that although effectiveness was still poorly demonstrated, this method had the potential to improve learning outcomes. An observer tool is a document which is used by observers during a scenario played by other learners and immediately compares the player's technical or non-technical skills with a referential guide. As it has been shown that observers learn less than those on the "hot seat" and as time for training is limited and the number of trainees is huge, focusing on observers is important. By visually assessing the practice of others repeatedly during the course and comparing each performance to the reference (i.e. the observer tool), the learner may increase his engagement in the training process with an expected final result of improved training efficacy. In a previous study performed in our simulation center, it has been have shown that using an observer tool increases immediate learning scores during operating room crisis management simulation. Good data on the use of such an observer tool in other training fields is needed to confirm these preliminary positive results.