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Heart Arrest clinical trials

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NCT ID: NCT03476720 Completed - Cardiac Arrest Clinical Trials

Improving Defibrillation Pad Position

Start date: May 1, 2018
Phase:
Study type: Observational

Manufacturer's diagrams showing defibrillation pad positioning (as used on public access defibrillators) are anatomically incorrect and are likely to lead to poor position of defibrillation pads, with reduced defibrillation efficacy. We will ask untrained members of the public to observe the diagrams and place pads as indicated on the diagram. We will asses the accuracy of pad placement and repeat the study using an anatomically correct diagram to see if we can improve the accuracy of pad placement.

NCT ID: NCT03464123 Completed - Clinical trials for Cardiac Arrest, Out-Of-Hospital

Brain Oxygenation During Cardiopulmonary Resuscitation

Start date: February 24, 2017
Phase:
Study type: Observational

The study is aimed to assess (a) the incidence of hyperoxia at the point of return of spontaneous circulation (ROSC) and (b) the role of arterial blood oxygen partial pressure to brain oxygenation during out-of-hospital cardiac arrest. 80 adult patients will be recruited in a physician staffed helicopter emergency medical services. Brain regional oxygen saturation and invasive blood pressure are monitored until hospital admission and arterial blood gases are analyzed immediately when the unit arrives to the patient and again at the time of ROSC.

NCT ID: NCT03452917 Completed - Clinical trials for Out-Of-Hospital Cardiac Arrest

Clinical Trial of Sodium Nitrite for Out of Hospital Cardiac Arrest

SNOCAT
Start date: February 8, 2018
Phase: Phase 2/Phase 3
Study type: Interventional

In this clinical study, a total of 1500 patients with out-of-hospital cardiac arrest in Seattle/King County will be enrolled. This will be a randomized clinical trial and patients will receive either two different doses of IV sodium nitrite (45 mg or 60 mg) or placebo during resuscitation in the field by paramedics. The primary outcome will be proportion of patients surviving to hospital admission.

NCT ID: NCT03443167 Completed - Clinical trials for Cardiopulmonary Arrest With Successful Resuscitation

Cardiopulmonary Resuscitation by Children

RCParvulari
Start date: January 25, 2018
Phase: N/A
Study type: Interventional

Children's education students are able to identify a possible emergency and in their case act appropriately. The authors think that the propsed training will improve the knowledge, change the attitude and improve their practical skills, and also retain the information over time.

NCT ID: NCT03423745 Completed - Clinical trials for Cardiopulmonary Arrest

Appropriate Number of Endotracheal Intubation Experience for CPR

Start date: March 1, 2007
Phase: N/A
Study type: Observational [Patient Registry]

This is a clinical study based on analysis of video-clip data of intubation and clinical data for cardiopulmonary resuscitation patients between 2011.03.01.-2012.02.28.. Aim of this study is to estimate the appropriate number of endotracheal intubation(ETI) experience for successful ETI at first attempt during cardiopulmonary resuscitation.

NCT ID: NCT03405467 Completed - Clinical trials for Cardiopulmonary Arrest With Successful Resuscitation

10-years Nationwide Alpine Accidents in Austria

Start date: January 21, 2015
Phase: N/A
Study type: Observational

This observational study intends to analyze the characteristic of specific accidents happened in Austrian's mountainous regions. The mechanisms of accidents which are evaluated are lightning accidents, cardiopulmonary resuscitation with or without automated external defibrillator, frostbite injuries, accidents with flying vehicle (e.g. paraglider, hang-glider…).

NCT ID: NCT03378518 Completed - Clinical trials for In-hospital Cardiac Arrest

Evaluation of Effectiveness of Blue Code Team After In-hospital Cardiopulmonary Arrest

Codeblue
Start date: January 1, 2016
Phase: N/A
Study type: Observational

This study aimed to retrospectively examine patients evaluated by the Code Blue team on a Code Blue call in our hospital between 2016-2017. Primary outcome: an examination of the survival rates and demographic data of the patients evaluated as an emergency by a Code Blue call in the period 2016-2017. Secondary outcome: to determine the rates of false Code Blue calls, the clinics giving Code Blue calls and the relationship between the times of Code Blue calls and mortality.

NCT ID: NCT03325452 Completed - Clinical trials for Cardio-respiratory Arrest, Prolactin

Evaluating Prognostic Contribution of Lactate on Recovery of Spontaneous Cardiac Activity After Cardiac Arrest

PROLAC
Start date: December 19, 2017
Phase: N/A
Study type: Interventional

Incidence of non-hospital cardio-respiratory arrest (ACR) in France is around 40 000 cases per year, with mortality remaining very high, with 75% of patients dying before arrival in hospital. The investigators know some validated predictive factors for recovery of spontaneous cardiac activity (RACS) such as age, no flow (time between ACR and onset of CPR), type of initial electrical activity (FV, TVSP), or the value of CO2 expired. However, the use of these prognostic criteria in the conduct of CPR maneuvering is in practice limited. Lactate is now a well-known prognostic biological marker used in many pathological conditions such as shock states or the severe traumatized patient. Some data have also demonstrated the prognostic value of lactate on morbidity and mortality after ACR after resumption of spontaneous cardiac activity. The hypothesis of our study is that the evaluation of the initial lactate in the early cardiopulmonary resuscitation could be a prognostic factor of RACS.

NCT ID: NCT03312296 Completed - Stent Thrombosis Clinical Trials

Definite Stent Thrombosis in Comatose Out of Hospital Cardiac Arrest Survivors

ST OHCA
Start date: August 1, 2016
Phase:
Study type: Observational

Reliable data on stent thrombosis (ST) in comatose out of hospital cardiac arrest (OHCA) survivors is lacking. In comatose OHCA survivors suspicion of ST can be made with precise clinical monitoring of the patient with definite confirmation being possible only by coronary angiography or autopsy of deceased patients. However in addition to definite ST which can be confirmed using current protocols, additional ST which are clinically silent are plausible. These could be identified only by systematic coronary angiography of all OHCA survivors or by autopsy of deceased patients. Collectively with definite ST confirmed by coronary angiography upon clinical suspicion the incidence of all forms of ST in survivors of OHCA treated with PCI and hypothermia could be obtained. Consecutive comatose survivors of OHCA treated with percutaneous coronary intervention (PCI) and hypothermia will be included. All study participants will receive treatment per our established clinical protocol and will be followed for 10 days. In all patients in whom clinical suspicion of ST will be made immediate coronary angiography and if necessary PCI will be carried out. In all patients that will die in the observed period of 10 days autopsy will be performed. Survivors however will have an additional control coronary angiography on 10th day after admission, to assess presence of clinically silent ST. We expect that the incidence of true definitive ST in comatose OHCA survivors treated with urgent PCI with stenting and hypothermia is greater than one, which is confirmed on the basis of clinical suspicion by angiography or later with autopsy.

NCT ID: NCT03310450 Completed - Oxidative Stress Clinical Trials

Tour de Borobudur Troponin Study on Predictors and Synergistic Role of MDA and Hs-CRP Levels

TdBTS
Start date: October 28, 2017
Phase:
Study type: Observational

Prospective observational study to determine predictors that related to cardiac troponin I (cTnI) release, malondialdehyde (MDA) and high sensitivity C Reactive Protein (hs-CRP) after Tour de Borobudur (TdB) 2017