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Hearing Loss clinical trials

View clinical trials related to Hearing Loss.

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NCT ID: NCT06019481 Recruiting - Clinical trials for Congenital Hearing Loss Secondary to Biallelic Mutations in the Otoferlin Gene (OTOF)

A Natural History Study in Pediatric Participants With Hearing Loss Due to OTOF, GJB2, or GJB2/GJB6 Mutations

ENSEMBLE
Start date: December 18, 2023
Phase:
Study type: Observational

This is an observational study to examine the characteristics of gene-related hearing loss in pediatric participants with biallelic otoferlin (OTOF) Mutations, Gap Junction Beta 2 (GJB2) Mutations, or Digenic GJB2/Gap Junction Beta 6 (GJB6) Mutations. This study will follow the participant for 4 years with annual visits each year.

NCT ID: NCT06016335 Completed - Hearing Loss Clinical Trials

MRI-based Synthetic CT Images of the Head and Neck

Start date: September 22, 2022
Phase: N/A
Study type: Interventional

In case of surgical procedures in the head and neck region, MRI in combination with CT of the bone is often the standard modality to visualise bony landmarks for planning, navigation and risk assessment. An important downside of a CT scan is the associated radiation exposure, especially in children. An additional downside is the sedation or general anaesthesia needed for both the MRI and CT scan session in very young children. These downsides could be removed if the CT scan can be substituted by an MRI sequence that can provide the same information as CT. This project aims to determine the feasibility of recreating CT like images of the craniofacial bones from MRI images using machine learning techniques.

NCT ID: NCT06013215 Not yet recruiting - Clinical trials for Sensorineural Hearing Loss

Electrical Impulse Parameters and Neuronal Population in the Cochlear Implanted Patient-PULSE

PULSE
Start date: November 1, 2023
Phase: N/A
Study type: Interventional

The cochlear implant provides good auditory performance despite high inter-individual variability, but performance in noise remains limited. Modification of the coding strategies could improve these performances. A better characterization of the remaining neuronal population by looking for the charge integration efficiency (which depends on the duration and the amplitude of the electrical pulse) would allow an optimization of the settings by adapting either the duration or the amplitude of the pulse according to the quality of the remaining neuronal population.

NCT ID: NCT06008782 Recruiting - Dementia Clinical Trials

HEARS-SLP: Providing SLP-Delivered Hearing Health Care to Individuals With Cognitive Impairment

Start date: December 15, 2023
Phase: N/A
Study type: Interventional

Building upon the HEARS audiologist-community health worker (CHW) model, this study intervention will be delivered by a speech-language pathologist (SLP). The primary objective of the study is to develop and test an affordable and accessible hearing rehabilitative intervention that will be delivered by a SLP to individuals with cognitive impairment.

NCT ID: NCT05993832 Recruiting - Deafness Clinical Trials

Word Learning in Deaf Children Using Eye-tracking and Behavioral Measures

Start date: August 7, 2023
Phase: N/A
Study type: Interventional

Mutual exclusivity is a word learning constraint in which the learner assumes that a given word refers to only one category of objects. In spoken languages, mutual exclusivity has been demonstrated in monolingual children as young as 17 months and cross-linguistically, while multilingual learners show an attenuated mutual exclusivity bias. Mutual exclusivity has not been robustly demonstrated in deaf children acquiring American Sign Language (ASL). Further, it is unclear if mutual exclusivity applies to those learning both a signed and a spoken language. Like unimodal bilinguals, bimodal bilingual (BiBi) children learn two words for an object, but these words are separated by modality. A BiBi child could therefore assume that all objects have two words (like unimodal bilinguals) or that all objects have one spoken word and one sign (within-modality mutual exclusivity). The goals of the current study are to demonstrate mutual exclusivity in monolingual deaf children acquiring ASL, and to determine if BiBi deaf children utilize mutual exclusivity within each modality.

NCT ID: NCT05973669 Not yet recruiting - Clinical trials for Hearing Loss, Sensorineural

MED-EL Remote Care Multi-Center Feasibility Study

Start date: September 2024
Phase: N/A
Study type: Interventional

MED-EL Remote Care is a way for MED-EL cochlear implant users to check their hearing and cochlear implant device from any location, without the need for a scheduled, in-person appointment with their audiologist. This study will assess the effectiveness, efficiencies, and useability of MED-EL Remote Care.

NCT ID: NCT05970445 Active, not recruiting - Hearing Loss Clinical Trials

Clinical Phenotypic Characteristics of SC26A4

Start date: May 15, 2023
Phase:
Study type: Observational

The presence or absence of SC26A4, whether combined with Mondini malformation, and patient age, are important factors affecting the degree of hearing loss in the Chinese population.

NCT ID: NCT05970211 Recruiting - Hearing Loss Clinical Trials

Early Age-Related Hearing Loss Investigation Pilot Study

P-EARLHI
Start date: June 19, 2023
Phase: N/A
Study type: Interventional

The purpose of this clinical trial pilot is to obtain feasibility and pilot data necessary to inform the hearing intervention being designed for a larger R01 clinical trial that seeks to determine whether best practice hearing aid intervention impacts hearing-related outcomes in adults with hearing loss aged 55 to 75 years. Secondary purposes include: To determine what effects best practice hearing aid intervention has on physical, social, and quality of life outcomes in adults with hearing loss aged 55 to 75 years.

NCT ID: NCT05964725 Recruiting - Clinical trials for Transcranial Direct Current Stimulation

The Study on Effect and Neural Network Mechanism of Transcranial Direct Current Stimulation for Sudden Deafness With Tinnitus

Start date: November 23, 2023
Phase: N/A
Study type: Interventional

This clinical study is prospective, single-center, randomized, controlled, double-blind clinical trail, which entitled transcranial electrical stimulation for the treatment of acute tinnitus approved by Sun Yat-sen University, and intends to recruit 86 patients with sudden deafness and tinnitus. For acute subjective tinnitus, a common otological disease, the study gave the experimental group patients received tDCS with electrodes positioned over the left temporal cortex for 5 days. To assess the efficacy of conventional medical therapy and tDCS by comparing changes in anterior and posterior tinnitus-related subjective scale scores, such as THI, VAS, BAI, BDI, PSQI, and hearing recovery, in patients who received tDCS, to determine whether tDCS is effective in improving acute tinnitus, and whether it is superior to conventional tinnitus treatment. In addition, the study will continue to follow patients for 1 month,3 months, and 6 months after the end of treatment to observe the long-term sustained efficacy of tDCS. This clinical trail will also evaluate tDCS from the perspective of compliance and safety, and explore the factors affecting the efficacy of this therapy.

NCT ID: NCT05962814 Not yet recruiting - Clinical trials for Hearing Impaired Children

EarGenie: Assessment of a Minimum Viable Product

Start date: August 14, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to evaluate safety and preliminary efficacy of a novel device (EarGenie MVP) to assess hearing function in infants, using a small number of infants with normal hearing. The main questions it aims to answer are: - Is our device safe? - Does the device provide preliminary results consistent with previous results from a commercial functional Near Infrared Spectroscopy (fNIRS) research device? Participants will attend one test session and have their hearing assessed with the EarGenie MVP device.