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Healthy Volunteers clinical trials

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NCT ID: NCT06109259 Recruiting - Healthy Volunteers Clinical Trials

Bioequivalence Study for the Safety and the Pharmacokinetics of DWJ1567 in Healthy Adult Volunteers

Start date: November 6, 2023
Phase: Phase 1
Study type: Interventional

This study aims to compare the pharmacokinetics and safety following administration of DWJ1567 and DWC202312 in healthy volunteers

NCT ID: NCT06103877 Recruiting - Healthy Volunteers Clinical Trials

A Placebo-controlled Safety and Tolerability Study of Intravenous (IV) and Subcutaneous (SC) AZD1163 in Healthy Volunteers

Start date: November 1, 2023
Phase: Phase 1
Study type: Interventional

A study to demonstrate the safety and tolerability of AZD1163 when administered intravenously and subcutaneously in healthy participants.

NCT ID: NCT06101316 Recruiting - Healthy Volunteers Clinical Trials

A Bridging Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of CB06-036 in Healthy Subjects in China

Start date: September 19, 2023
Phase: Phase 1
Study type: Interventional

CB06-036 is an investigational drug developed by Shanghai Zhimeng Biopharma Inc. for the treatment of Chronic Hepatitis B.

NCT ID: NCT06093659 Recruiting - Healthy Volunteers Clinical Trials

Nicotine Pharmacokinetic Study of Heated Tobacco and Heated Herbal Products

Start date: July 7, 2023
Phase: N/A
Study type: Interventional

This is a randomised, cross-over, open-label, confinement study conducted in 25 adult male or female smokers of combustible cigarettes (CCs). The study investigates combustible cigarettes, heated tobacco products (HTPs), and Heated Herbal Products (HHPs), with endpoints including pharmacokinetic evaluation, and subjective effects. Subjects will perform a Screening Visit and one Study Visit, including a 6-day confinement period.

NCT ID: NCT06081465 Recruiting - Healthy Volunteers Clinical Trials

A Phase I Study of Single and Multiple Doses of VG290131 in Healthy Subjects

Start date: October 20, 2023
Phase: Phase 1
Study type: Interventional

This is a randomized, double-blind, placebo-controlled phase I study to evaluate the safety, tolerability and PK profiles of orally administered VG290131 in healthy subjects. The main questions it aims to answer are: 1. The safety and tolerability of VG290131 when administered orally as a single dose and multiple doses in healthy subjects. 2. The pharmacokinetic (PK) profiles of VG290131 and the food effect on the PK profiles of VG290131 in healthy subjects. Approximately 86 subjects will be enrolled in the study.

NCT ID: NCT06067490 Recruiting - Healthy Volunteers Clinical Trials

A Phase I Study of RC1416 Injection

Start date: July 3, 2023
Phase: Phase 1
Study type: Interventional

This is a phase I study to evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of RC1416 injection via Subcutaneous Administration in Healthy Adult Volunteers.

NCT ID: NCT06066281 Recruiting - Healthy Volunteers Clinical Trials

Validation of the Consecutive-Letter Substitution Task (CST)

Start date: January 3, 2023
Phase:
Study type: Observational

The CST is a new neuropsychological test created to measure information processing speed, which is frequently impaired in patients with multiple sclerosis. The aim of the study is to validate the CST through the administration on a representative sample of healthy subjects of the Italian population. Each subject will be administered a standardized battery of neuropsychological tests (Digit Span Task and Brief Repeatable Battery of Neuropsychological Tests which includes Selective Reminding Test, Spatial Recall Test, Symbol Digit Modalities Test, Paced Auditory Serial Addition Test and Word List Generation), and the CST in order to verify its validity. After 15 days from the baseline, the CST will be re-administrated to all subjects to assess the reliability of the test.

NCT ID: NCT06066099 Recruiting - Healthy Volunteers Clinical Trials

Single Ascending Dose, Multiple Ascending Dose, Food Effect Study With AP31969

Start date: October 4, 2023
Phase: Phase 1
Study type: Interventional

The primary objective of the study is to evaluate the safety and tolerability of single doses (Part A) and multiple doses (Part B) of AP31969 in healthy participants.

NCT ID: NCT06060067 Recruiting - Healthy Volunteers Clinical Trials

A Study of Dengue Vaccine in Healthy Children, Teenagers and Adults in India

Start date: March 29, 2024
Phase: Phase 3
Study type: Interventional

The main aims of the study are to learn about side effects and a participant's immune response to Takeda's Dengue Vaccine when given twice within 3 months. Participants will receive 2 doses of their randomized treatment (vaccine or placebo). Children, teenagers and adults will receive one dose of either the vaccine or placebo on Day 1 and the second dose of either the vaccine or placebo 3 months later. Up to 4 blood samples will be taken throughout the study. During the study, participants will visit their study clinic 6 times.

NCT ID: NCT06050915 Recruiting - Healthy Volunteer Clinical Trials

A Study of DISC-3405 in Healthy Volunteers

Start date: October 3, 2023
Phase: Phase 1
Study type: Interventional

This phase 1 study will assess the safety, tolerability, pharmacokinetics, pharmacodynamics and immunogenicity of DISC-3405 in adult male and female healthy volunteers.