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Healthy Volunteers clinical trials

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NCT ID: NCT06344065 Recruiting - Healthy Volunteers Clinical Trials

Immunogenicity and Safety of Diphtheria, Tetanus, Pertussis (DTaP) Vaccine in 3-month-old Infants

Start date: December 21, 2023
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and immunogenicity of the DTaP in 3-month-old infants.

NCT ID: NCT06343714 Not yet recruiting - Healthy Volunteers Clinical Trials

A Study of FB1003 in Healthy Subject

Start date: April 3, 2024
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate safety and tolerability of FB1003 when given subcutaneously to healthy participants. Blood tests will be done to examine blood exposure, concentration and half-life of FB1003 following administrations. For each participant, the study will last up to about 12 weeks for single ascending dose part, and 18 weeks for multiple ascending dose part, including screening.

NCT ID: NCT06342713 Not yet recruiting - Healthy Volunteers Clinical Trials

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single- and Multiple-Ascending Doses and Food Effect of BGB-45035

Start date: May 28, 2024
Phase: Phase 1
Study type: Interventional

This study is the first-in-human (FIH) study for BGB-45035. The study will evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of BGB-45035 with both a single dose and multiple doses administered at different dose levels in healthy participants. Study details include: - The study duration will be up to 16 months. - The treatment duration will be up to 14 days. - Safety follow-up 30 days after last dose of study drug.

NCT ID: NCT06342700 Recruiting - Healthy Volunteers Clinical Trials

A Food Effect and Relative Bioavailability Study of Rilzabrutinib in Healthy Participants

Start date: March 25, 2024
Phase: Phase 1
Study type: Interventional

This is a cross-over, Phase 1, 4-arm study. The purpose of this study is to measure the relative bioavailability and food effect of crystalline formulation rilzabrutinib and amorphous formulation rilzabrutinib in healthy male and female participants aged 18 to 55 years of age. The total study duration per participant is expected to be up to 36 days, including: - Screening: up to 4 weeks - Treatment periods: once successfully screened, enrolled participants will be randomized to 1 of 4 treatment sequences with 4 single dose treatment periods. - Washout: One day washout is planned after each treatment period hence providing 2 days between doses. - Safety follow-up: participants will be asked to participate in an end-of-study safety assessment upon discharge from the clinical study unit, ie, on Day 8 of the study.

NCT ID: NCT06339788 Not yet recruiting - Healthy Volunteers Clinical Trials

Pharmacokinetics of HD-P023 and Co-administration of Teneligliptin and Empagliflozin High in Healthy Volunteers

Start date: April 2024
Phase: Phase 1
Study type: Interventional

The purpose of this study is to compare the pharmacokinetics and safety of HD-P023 and coadministration of Teneligliptin and Empagliflozin in healthy adult volunteers

NCT ID: NCT06337500 Not yet recruiting - Healthy Volunteers Clinical Trials

Validation of a Making Decision Hybrid (Ecologic and Virtual) Task

LABLife
Start date: June 1, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to validate a new hybrid (ecological + virtual) decision-making tool. The difference in behavior (risky choices) between the "hybrid" task and the "virtual" task will be evaluated.

NCT ID: NCT06337422 Not yet recruiting - Healthy Volunteer Clinical Trials

Bioequivalence Study of Generic Celecoxib 200 mg Capsules

Start date: September 23, 2024
Phase: Phase 1
Study type: Interventional

To determine and compare the rate and extent of absorption of a test formulation with that of a reference innovator formulation when given as equal labeled dose in healthy subjects under fasting conditions

NCT ID: NCT06337409 Not yet recruiting - Healthy Volunteer Clinical Trials

Bioequivalence Study of Empagliflozin 25 mg Film-coated Tablets in Healthy Thai Volunteers

Start date: July 1, 2024
Phase: Phase 1
Study type: Interventional

To determine and compare the rate and extent of absorption of a test formulation with that of a reference innovator formulation when given as equal labeled dose in healthy subjects under fasting conditions

NCT ID: NCT06336005 Recruiting - Healthy Volunteers Clinical Trials

A Study to See How Safe a New Medicine (NNC6022-0001) is in Healthy People

Start date: March 28, 2024
Phase: Phase 1
Study type: Interventional

The study is testing a new study medicine, which is being tested as a potential medicine to treat cardiometabolic diseases. The aim of this study is to see if the study medicine is safe, how it works in participants body, and what the body does to the study medicine. Participants will either get NNC6022-0001 (the new study medicine) or placebo (a "dummy medicine" without the active ingredient). Which treatment participants get is decided by chance. The study medicine is a potential new medicine which cannot be prescribed by doctors. The study will last for about 10 months in total.

NCT ID: NCT06335134 Recruiting - Healthy Volunteers Clinical Trials

A Drug-Drug Interaction Study Between XW003 and Metformin, Warfarin, Rosuvastatin or Digoxin

Start date: July 14, 2023
Phase: Phase 1
Study type: Interventional

This is a study of a drug-drug interaction between XW003 and Metformin, Warfarin, Rosuvastatin or Digoxin