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Healthy Volunteers clinical trials

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NCT ID: NCT06254235 Completed - Healthy Volunteers Clinical Trials

Bioequivalence Study of Two Octreotide Microsphere Formulations in Healthy Volunteers

Start date: June 16, 2021
Phase: Phase 1
Study type: Interventional

The goal of this clinical trial is to evaluate the pharmacokinetic characteristics of two octreotide microsphere formulations in healthy Chinese volunteers. Participants will receive single-dose of either test or reference octreotide microsphere formulations. Researchers will compare pharmacokinetic characteristics of the two formulations to see if they are bioequivalent.

NCT ID: NCT06254209 Recruiting - Healthy Volunteers Clinical Trials

Study to Evaluate the Physiological Effects on the Skin of 3 Food Supplements Versus Placebo in 40-60 Years Old Female Subjects

Start date: November 6, 2023
Phase: N/A
Study type: Interventional

The objective is to evaluate the effects on the skin of 3 foods supplements compared to placebo after daily intake for 3 months in female subjects presenting healthy skin. Skin parameters measured are: the firmness of the skin and other biomechanical skin properties (elasticity, tonicity, density), cellulitis visibility, radiance complexion, skin condition (microrelief, skin barrier function and moisturizing)

NCT ID: NCT06251024 Recruiting - Healthy Volunteers Clinical Trials

Study of a Respiratory Syncytial Virus Candidate Formulation in Adults Aged 60 Years and Older

Start date: April 2, 2024
Phase: Phase 2
Study type: Interventional

The purpose of this Phase IIb study is to evaluate the efficacy of the RSV vaccine candidate for the prevention of lower respiratory tract disease (LRTD) due to RSV. The study will enroll approximately 4500 adults aged 60 years and older in a 1:1 ratio to receive a single intra-muscular (IM) administration of either a pre-determined dose of the RSV vaccine candidate or placebo.

NCT ID: NCT06250205 Recruiting - Healthy Volunteers Clinical Trials

Evaluate the Pharmacokinetics of a Combined Oral Contraceptive (COC) With and Without Obicetrapib

Start date: February 5, 2024
Phase: Phase 1
Study type: Interventional

A study to evaluate the impact of Obicetrapib on the PK levels of Drospirenone and Ethinyl Estradiol (COC) in 30 adult female, healthy volunteers.

NCT ID: NCT06247670 Recruiting - Healthy Volunteers Clinical Trials

Study of CMP-CPS-001 in Healthy Volunteers

Start date: February 5, 2024
Phase: Phase 1
Study type: Interventional

The objective of this clinical study is to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of single and multiple ascending doses of CMP-CPS-001 administered as a subcutaneous injection in adult healthy volunteers.

NCT ID: NCT06247644 Completed - Healthy Volunteers Clinical Trials

BD Evolve™ On-body Injector's Adherence Performance - Wear Study

Start date: February 14, 2024
Phase: N/A
Study type: Interventional

An On-body Injector is a small device, which is adhered to the skin with a sticky patch. The injector is intended to deliver a small volume of medicine from a reservoir inside the device into the skin via a small catheter. The drug delivery happens after a period of time, as programmed into the device, and afterwards the device can be removed. The purpose of this study is to evaluate how well the BD Evolve™ On-body Injector adhesive pad sticks to the skin and how the adhesive keeps the device in position when worn on the arm during normal daily activities for 28 hours. As this study only evaluates the performance of the adhesive pad of the OBI, no injection will be performed, and the device will not be filled with any fluid. The injection capability will be disabled.

NCT ID: NCT06246695 Completed - Healthy Volunteers Clinical Trials

A Study to Evaluate the Effect of Itraconazole and Rifampicin on the Pharmacokinetics of Jaktinib in Healthy Volunteers

Start date: October 27, 2021
Phase: Phase 1
Study type: Interventional

The primary objective of this study was to assess the effect of rifampicin and itraconazole, on the pharmacokinetics (PK) of Jaktinib in healthy Volunteers.

NCT ID: NCT06244472 Not yet recruiting - Healthy Volunteers Clinical Trials

A New Generation of Magnetoencephalographs for High Speed Functional Brain Imaging

DEMAGUS
Start date: February 15, 2024
Phase: N/A
Study type: Interventional

The goal is to perform a first evaluation of the capabilities of a new generation of non-invasive magnetoencephalography whole head device using optically pumped magnetometers using Helium 4 as the sensitive element (OPM He4) to record brain magnetic activities. The investigators will record 1) healthy subjects stimulated with visual, auditory, somesthesic and motor stimuli and 2) athletes who suffered a mild concussion. The main hypothesis is that the OPM magnetoencephalographs (MEG) system will be able to detect brain activity. The secondary hypothesis is that the data recorded with the OPM MEG system will allow to reconstruct maps of the brain activity. To test the main hypothesis, they will compare the signal to noise ratio of brain activities between a classical MEG system and the new OPM He4 MEG. The secondary hypothesis will be tested through a comparison of the maps of brain activity obtained thanks to the data recorded with a classical MEG system and the new OPM He4 MEG.

NCT ID: NCT06244407 Not yet recruiting - Healthy Volunteer Clinical Trials

The Bioequivalence Study of Fixed-dose Combination of Vildagliptin and Metformin HCI 50/1000 mg FCT Under Fed Conditions

Start date: May 23, 2024
Phase: Phase 1
Study type: Interventional

To determine and compare the rate and extent of absorption of a test formulation with that of a reference innovator formulation when given as equal labeled dose in healthy subjects under fed conditions

NCT ID: NCT06243809 Not yet recruiting - Healthy Volunteer Clinical Trials

The Bioequivalence Study of Linagliptin 5 mg Film-coated Tablet in Healthy Thai Volunteers

Start date: April 24, 2024
Phase: Phase 1
Study type: Interventional

A Single Dose, Randomized, Open-label, Two-way Crossover Bioequivalence Study of Generic Linagliptin 5 mg Film-coated Tablet (LINIPTIN) and Reference Product (Trajenta®) in Healthy Thai Volunteers under Fasting Conditions